“…This result is consensual as it is independent from the specific method used: it has been reported using radial atrophy (Frisoni et al, , 2006Scher et al, 2007), large deformation high-dimensional brain mapping (Csernansky et al, 2000;Tang et al, 2014;Tepest et al, 2008;Wang et al, 2006Wang et al, , 2003, spherical harmonics (Gerardin et al, 2009;Lindberg et al, 2012) or a VBM-based analysis (Chételat et al, 2008); see Figure 1 for an illustration. In some studies, abnormalities were also found in medial regions of the surface, mostly corresponding to the (pre)subiculum (Frisoni et al, , 2006Wang et al, 2006) or even in all subfields Chow et al, 2012Chow et al, , 2015.…”