2017
DOI: 10.23822/eurannaci.1764-1489.17
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Histamine release positive test associates with disease remission in chronic spontaneous urticaria: a proof-of-concept study

Abstract: Summary Background. Histamine release (HR) test has previously been shown to predict the presence of endogenous histamine-releasing factors in chronic spontaneous urticaria (CSU

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Cited by 8 publications
(7 citation statements)
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“…However, the clinical response to omalizumab was the same in patients with a positive urticaria HR test compared to patients with a negative urticaria HR test. In a recent study by Berti et al ., similar observations were reported. However, a larger reduction in disease activity and a more frequent spontaneous disease remission at 12 months were reported by patients with a positive urticaria HR test.…”
Section: Discussionsupporting
confidence: 82%
“…However, the clinical response to omalizumab was the same in patients with a positive urticaria HR test compared to patients with a negative urticaria HR test. In a recent study by Berti et al ., similar observations were reported. However, a larger reduction in disease activity and a more frequent spontaneous disease remission at 12 months were reported by patients with a positive urticaria HR test.…”
Section: Discussionsupporting
confidence: 82%
“…This is the first description of French patient-control group of patients with CU, in the real life. The population we observed appeared to be very similar in age, higher frequency of females, frequent dermographism and overweight distribution as other populations described in other international [36,37,[41][42][43][44][45] or French [46,47] studies. The mean duration of the disease was quite long but this does not mean it was due to a delayed diagnosis as most of patients already have had 2 or 3 lines of treatment and were addressed to the local reference center because of difficulties in controlling the disease.…”
Section: Discussionsupporting
confidence: 82%
“…We could not compare data with autologous serum or plasma skin tests (ASST and APST), as these are not routinely performed in our country. According to the findings of Berti et al, there does not seem to be any association between in vivo and in vitro tests in patients with CU (19), and the same could be true for AE. The performance of ASST and APST would be desirable to study in the future, to confirm these findings also in mono-symptomatic AE.…”
Section: Resultsmentioning
confidence: 92%