2024
DOI: 10.3390/transplantology5020009
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Histocompatibility Testing: A Fundamental Aspect of Renal Transplant Workup

Vikash Chandra Mishra,
Dinesh Chandra,
Vimarsh Raina

Abstract: Histocompatibility testing is pivotal in any renal transplantation workup, aimed at enhancing prospective donor recipient compatibility and improving transplant outcomes. The evolution and advancement of histocompatibility testing, particularly HLA typing, have significantly improved its precision. This study outlines the historical progression from serologic to DNA-based HLA typing, emphasizing the role of HLA proteins in immune response. Anti-HLA antibodies, targeting HLA proteins, pose challenges in renal t… Show more

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