Histological changes in male accessory reproductive organs in rats exposed to cigarette smoke and the protective effect of honey supplementation

Abstract

The effect of cigarette smoke (CS) on histology of male accessory reproductive organs and the possible protective effect of honey supplementation in rats were investigated in this study. Rats received distilled water, honey, CS exposure or honey plus CS exposure. Honey (1.2 g/kg body weight/day) was administered by gavage and CS exposure (3 times per day) was done in a chamber for 13 weeks. CS exposure significantly increased relative weight of epididymis and ventral prostate. There were also significantly increased number of clear cells and epithelial height of cauda epididymis as well as severe interstitial oedema and decreased epithelial height of prostate gland. However, with the supplementation of honey, these histological changes were significantly reversed suggesting the protective effect of honey against the toxic effect of CS on male accessory reproductive organs in rats.

Qualitative and Quantitative Estimation of Phytoconstituents in Trigonella Foenum Graceum

“…In Chinese traditional medicine, the seeds of this plant have been prescribed as a tonic for stomach disorders, and the whole aerial part of the plant is used as a folk medicine for the treatment of renal diseases in the Northern-East region of China. Many phytochemical studies on constituents of the seeds have been reported 5 . The name fenugreek comes from foenum-graecum, meaning Greek hay, as the plant was traditionally used to scent inferior hay 6 .…”

Diabetes mellitus-induced male reproductive impairment: The role of natural products: A review

“…To date, a lot of research has been done to study the role of different natural products in male reproductive functions (Mohamed et al, 2011;Mohamed et al, 2012;Mohamed et al, 2013). Some studies have used whole plant extracts, thus taking advantage of the abundance of different phytochemicals which have several intervention targets, while others have used specific compounds isolated from plants.…”