2014
DOI: 10.33762/bvetr.2014.98805
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Histopathologic Changes in Rat Organs Upon Chronic Exposure to Formaldehyde Vapor

Abstract: The present study was carried out to detect histopathologic lesions in different rat organs after chronic exposure to formaldehyde vapor. Forty adult albino Wistar rats were used in this experiment. Animals were divided into two groups; Control group (n=10; 5 males and 5 females) which were not exposed to formaldehyde at all, while the remainders regarded as the experimental group (exposed to formaldehyde for 21 days, n=30; 15 males and 15 females). The histopathologic examination in our study revealed several… Show more

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Cited by 4 publications
(2 citation statements)
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“…Lung sections from the rats exposed to formaldehyde revealed pulmonary changes in the architecture of the lung and an increase in collagen contents, these alterations were in agreement with what was observed in the rabbit's lungs after 40% exposure (Chinedum et al, 2014), also detected in rats (Mehdi et al, 2014;Ismail et al, 2021) and mice (Afrin et al, 2016). Also study (Ouies & Abd El-Naeem, 2020 ), showed the effect of formaldehyde on the natural structure of the lung and its immune expression.…”
Section: Histological Studysupporting
confidence: 79%
“…Lung sections from the rats exposed to formaldehyde revealed pulmonary changes in the architecture of the lung and an increase in collagen contents, these alterations were in agreement with what was observed in the rabbit's lungs after 40% exposure (Chinedum et al, 2014), also detected in rats (Mehdi et al, 2014;Ismail et al, 2021) and mice (Afrin et al, 2016). Also study (Ouies & Abd El-Naeem, 2020 ), showed the effect of formaldehyde on the natural structure of the lung and its immune expression.…”
Section: Histological Studysupporting
confidence: 79%
“…Lung sections from the rats exposed to formaldehyde revealed pulmonary changes in the architecture of the lung and an increase in collagen contents, these alterations were in agreement with what was observed in the rabbit's lungs after 40% exposure (Chinedum et al, 2014), also detected in rats (Mehdi et al, 2014;Ismail et al, 2021) and mice (Afrin et al, 2016). Also study (Ouies & Abd El-Naeem, 2020 ), showed the effect of formaldehyde on the natural structure of the lung and its immune expression.…”
Section: Histological Studysupporting
confidence: 79%