Histopathological and Immunohistochemical Profile of Benign and Malignant Oral Vascular Lesions.

Aguirre, Rodelio L.; Nishioka, Mai; Esguerra, Renelson L.; Wang, Lihong; Arai, Naoya; Okada, Norihiko; Amagasa, Teruo

doi:10.3353/omp.11.97

Cited by 3 publications

(1 citation statement)

References 26 publications

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“…Overall, IHC assessment confirmed the typical indicators of vascular neoplasm, namely, the increased expression of VEGF and Ki-67. 28 Moreover, in those with hemangiomas, endothelial markers, such as CD31, CD34, ERG, FLI1, and factor VIII, are strongly positive. Hemangiomas are negative for D2-40, a selective endothelial marker.…”

Section: Discussionmentioning

confidence: 99%

Three Cases of Parotid Hemangiomas in Adults

Huang

Lee

et al. 2021

Ear Nose Throat J

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Hemangiomas account for only 0.4% to 0.6% of all parotid tumors, making them extremely rare in adults. Unlike pediatric parotid hemangiomas, those in adults typically present as asymptomatic swellings of the parotid, have no skin discoloration, and usually do not regress spontaneously. Therefore, an accurate diagnosis of parotid hemangiomas in adults before surgical excision is generally challenging. Herein, we present 3 cases of adult parotid hemangiomas. The patients all received parotidectomies with tumor resection. Histopathological analysis of the resected specimens revealed numerous dilated, thin- or thick-walled (small, large, or variably sized) vessels lined with flattened endothelial cells. A diagnosis of cavernous hemangioma of the parotid gland was established only after the histopathological analysis. Parotid cavernous hemangiomas in adults are rare and often misdiagnosed before surgical resection. Clinical presentation and imaging features on ultrasonography, computed tomography, magnetic resonance imaging, and angiography may support an accurate preoperative diagnosis. Surgical resection proved a suitable treatment approach for our 3 cases.

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Section: Discussionmentioning

confidence: 99%

Three Cases of Parotid Hemangiomas in Adults

Huang

Lee

et al. 2021

Ear Nose Throat J

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Epulises: current problem

Burdina

Turin

2020

Parodontologiâ

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Relevance. Nowadays an important problem in dentistry is the early diagnosis and the treatment of tumors and tumor-like lesions. One of the most frequent lesions of the orofacial region, and particularly of the periodontium, is a non-tumor lesion called epulis. Some tumors and tumor-like lesions may be both clinically and histologically similar, hence the diagnosis and the differential diagnosis of the epulis is still complicated and need to pay attention. Moreover, every type of epulis has particular histological features that make a clinician use a specific treatment in each clinical case. The treatment success and the necessity of the further observations are determined by the correct diagnosis. However, there is still controversial data about epulis diagnosis. Moreover, the reliable criteria for correct diagnosis of each type of epulis have not been discussed yet.Purpose. The aim of this study is to determine the most relevant methods for differential diagnosis of every type of epulis and other tumor and tumor-like lesions of the alveolar ridge with the same clinical and histological descriptions was performed.Materials and methods. In this article the review of the literature is presented. A comprehensive literature search of the studies from 1970 through 2019 in PubMed database regarding the epulis and other tumor and tumor-like lesions with the same clinical and histological descriptions was performed. 71 relevant articles were selected.Results. “Epulis” is a term that refers to tumor and tumor-like lesions of the alveolar ridge. Due to their morphological features it is frequently necessary to carry out not only the histological studies but also use immunohistochemical and genetic analyses. It is not complicated to verify vascular epulis and fibrous epulis. If there is a plasma-cell infiltration of fibrous epulis stroma, clinician is to differ it from IgG4-assosiated diseases. In some cases to discern pyogenic granuloma and hemangioma it is necessary to carry out immunohistochemical study of the blood vessel wall components. It is also important to know diagnostics of giant-cell epulis. Here to divide peripheral and central giant-cell granulomas genetic analysis should be carried out.Conclusion. Usually microscopic study of fibrous and vascular epulis helps to differentiate it with other lesions. The IgG4associated diseases are to exclude by immunohistochemical study. Diagnostics of giant-cell epulis may include both immunochemical and genetic studies. Methods presented in this article are important both for treatment and for prognosis of the disease.

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A Comparative Histopathological and Immunohistochemically Study of Capillary Hemangioma, Pyogenic Granuloma and Cavernous Hemangioma in the Oral Region: with Special Reference to Vascular Proliferation Factors

Kawachi

2011

Int J Oral-Med Sci

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Histopathological and Immunohistochemical Profile of Benign and Malignant Oral Vascular Lesions.

Abstract: pathological and immunohistochemical profile of benign and malignant oral vascular lesions.

Cited by 3 publications

References 26 publications

Three Cases of Parotid Hemangiomas in Adults

Three Cases of Parotid Hemangiomas in Adults

Epulises: current problem

A Comparative Histopathological and Immunohistochemically Study of Capillary Hemangioma, Pyogenic Granuloma and Cavernous Hemangioma in the Oral Region: with Special Reference to Vascular Proliferation Factors

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