Histopathological changes after treatment of Mycoplasma bovis infected Does with Zinc oxide nanoparticles as a new tool.

Fathi, Afshin; Almuhammady, Abdulsalam K.; Sobhy, Mona; El-Miniawy, H.; Khattab, Marwa S.

doi:10.21608/ejvs.2019.19940.1133

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…Mycoplasma gallisepticum is a member of Mycoplasma genus and belongs to the Mollicutes class, which means "soft skin" in Latina, the simplest self-proliferating microbe, phylogenetically related low G+C (Gram+) bacteria, they are cell wallless microorganisms with genome size ranging from 500-1500 kilobase pairs (kbp) [1,2]. Representatives of the Mollicutes class are immune to most antimicrobial drugs, including beta-lactam antibiotics, glycopeptides and fosfomycin, since they lack cell walls [3,4]. MG is capable of taking on variety of forms.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Isolation and Polymerase Chain Reaction in Diagnosis of Mycoplasma Gallisepticum in Broiler Chickens in Kirkuk Governorate, Iraq

Hamdon,

Noomi,

AL-Rasheed

2024

Egyptian Journal of Veterinary Sciences

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HE objective of this study was to evaluate isolation, and evaluate the polymerase chain reaction (PCR) technique to confirm diagnosis of Mycoplasma gallisepticum (MG) in broiler chickens. One of the finest independent organisms is MG, can be reproduced autonomously, the lack of a cell wall, allowed it to take on various shapes and sizes, and to resist cell-wall targeting antibiotics. When MG infect chickens it caused chronic respiratory disease (CRD), characterized by rales, sneezing, coughing, nasal discharges, dyspnea, conjunctivitis. Decreased feed intake, feed conversion, an increase in mortality, carcass damage and medication costs, causing high economic losses. Diagnosing the cause is the first step in treatment, for evaluation isolation and direct PCR a total of 180 tracheal swabs were collected from broiler chickens (28-40) days old who had symptoms of CRD, during the period (1/12/2022-28/2/2023). Prevalence of MG by, isolation and direct PCR was 30.5% (55/180) and 32.77% (57/180) respectively. The sensitivity and specificity of direct PCR were 100% and 96.8% respectively. When comparing culturing with PCR , the study found that the sensitivity and specificity were 93% and 100% respectively. The study concluded that culturing is still the golden standard test for MG detection for its high sensitivity and specificity but takes a long time, direct PCR is very fast and efficient.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Isolation and Polymerase Chain Reaction in Diagnosis of Mycoplasma Gallisepticum in Broiler Chickens in Kirkuk Governorate, Iraq

Hamdon,

Noomi,

AL-Rasheed

2024

Egyptian Journal of Veterinary Sciences

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Mycoplasmas as Host Pantropic and Specific Pathogens: Clinical Implications, Gene Transfer, Virulence Factors, and Future Perspectives

Dawood

Algharib

Zhao

et al. 2022

Front. Cell. Infect. Microbiol.

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Mycoplasmas as economically important and pantropic pathogens can cause similar clinical diseases in different hosts by eluding host defense and establishing their niches despite their limited metabolic capacities. Besides, enormous undiscovered virulence has a fundamental role in the pathogenesis of pathogenic mycoplasmas. On the other hand, they are host-specific pathogens with some highly pathogenic members that can colonize a vast number of habitats. Reshuffling mycoplasmas genetic information and evolving rapidly is a way to avoid their host’s immune system. However, currently, only a few control measures exist against some mycoplasmosis which are far from satisfaction. This review aimed to provide an updated insight into the state of mycoplasmas as pathogens by summarizing and analyzing the comprehensive progress, current challenge, and future perspectives of mycoplasmas. It covers clinical implications of mycoplasmas in humans and domestic and wild animals, virulence-related factors, the process of gene transfer and its crucial prospects, the current application and future perspectives of nanotechnology for diagnosing and curing mycoplasmosis, Mycoplasma vaccination, and protective immunity. Several questions remain unanswered and are recommended to pay close attention to. The findings would be helpful to develop new strategies for basic and applied research on mycoplasmas and facilitate the control of mycoplasmosis for humans and various species of animals.

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Histopathological changes after treatment of Mycoplasma bovis infected Does with Zinc oxide nanoparticles as a new tool.

Abstract: Histopathological changes after treatment of Mycoplasma bovis infected Does with Zinc oxide nanoparticles as a new tool.

Cited by 2 publications

References 14 publications

Evaluation of Isolation and Polymerase Chain Reaction in Diagnosis of Mycoplasma Gallisepticum in Broiler Chickens in Kirkuk Governorate, Iraq

Evaluation of Isolation and Polymerase Chain Reaction in Diagnosis of Mycoplasma Gallisepticum in Broiler Chickens in Kirkuk Governorate, Iraq

Mycoplasmas as Host Pantropic and Specific Pathogens: Clinical Implications, Gene Transfer, Virulence Factors, and Future Perspectives

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