Histopathological Study of Peripheral Nerve Sheath Tumors.

Abstract

Accurate pathological designation of peripheral nerve tumors is important as there is dramatic difference in clinical outcome between benign and malignant tumors.Objective was to classify peripheral nerve sheath tumors as benign and malignant and to study the distribution of peripheral nerve sheath tumors among different age groups, sex and different anatomical locations. The study includes patients clinically diagnosed and treated for peripheral nerve sheath tumours from Dr. D. Y. Patil Hospital and Research center, Kolhapur. Sample size: 50 cases. Haematoxylin and Eosin stained sections were examined microscopically and histological interpretation were done. IHC was performed as per requirement. This study was conducted between May 2014 to may 2016. 49 out of 50 cases of peripheral nerve sheath tumors were benign, occurring more commonly than MPNST.PNSTs showed almost equal predilection for both the sexes. PNSTs occurred over a wide age range most common between 2nd and 4th decade of life.