Historical Introduction: Evolution of Knowledge of the Fungi and Mycoses from Hippocrates to the Twenty-First Century

Drouhet, E.

doi:10.1002/9780470688618.taw0128

Cited by 4 publications

(5 citation statements)

References 153 publications

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“…(11) In an another five-year study from south India, there were 63 biopsies diagnosed as FRS (31.7%) out of 138 biopsies of CRS in the study period. (12) Seventy-seven percent of fungal rhinosinusitis was caused by Aspergillus sp., and A. flavus (61.5%) was the most common isolate, a finding that is supported by a study from Iran (7) and by various studies from other parts of India. (6,13) In a similar study by S. Prateek et al, Aspergillus sp.…”

Section: Resultssupporting

confidence: 62%

“…CRS is characterised by sinonasal mucosal inflammation with a history of atleast 12 weeks of persistent symptoms and signs despite maximal medical therapy. (7) There is emerging evidence that fungi play an important role in exacerbation and perpetuation of mucosal inflammation in CRS, and only in more recent times has the categorization of FRS been more fully defined.…”

Section: Resultsmentioning

confidence: 99%

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Study on Chronic Rhinosinusitis: A Clinico-Mycological Perspective in a Tertiary Care Centre

Syiemlieh¹,

Mariraj²

2020

Int.J.Curr.Microbiol.App.Sci

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Chronic Rhinosinusitis (CRS) is a group of multifactorial diseases characterised by inflammation of the mucosa of the nose and paranasal sinuses with a history of at least 12 weeks of persistent symptoms and signs despite maximal medical therapy. Fungi are being increasingly implicated in the etiopathology of chronic rhinosinusitis. Early diagnosis and accurate classification of fungal rhinosinusitis which depends on demonstration of fungus may help in directing appropriate antifungal therapy. Objectives: This study was undertaken to determine the prevalence of fungal agents involved in chronic rhinosinusitis (CRS) and to analyse its clinico-mycological profile. Fifty patients with clinical suspicion of CRS attending a tertiary care hospital during a 6 months period were included in this analysis. The sino-nasal specimens were collected from patients attending ENT department which included allergic mucin, mucopurulent exudate at sinus cavity, nasal exudate and tissue specimens collected by endoscopic sinus surgery; while a portion of surgically excised specimens were received in sterile normal saline, another part of the specimens in 10% formalin were sent to the histopathology laboratory. These were subjected to microscopy by KOH mount and fungal culture as per standard mycological technique. Tissue specimens were also subjected to histopathological examination for correlation and categorization of fungal rhinosinusitis (FRS). Male to female ratio was 1.27:1; age varied from 14 years to 64 years with majority of patients (66%) belonging to age group 21-40 years. The prevalence of FRS was 26%, and 76.9% of it was caused by Aspergillus spp. Aspergillus flavus (61.5%) was the most prevalent fungus isolated, followed by Aspergillus niger (15.3%), Mucor spp. (15.3%) and Curvularia spp. (7.6%) respectively. Non-invasive allergic fungal rhinosinusitis (AFRS) was the most common presentation (85%). FRS is a continuous spectrum of disease varying in presentation, treatment and long-term sequelae. Clinical suspicion of fungal sinusitis should be made in those patients presenting with CRS with the following signs and symptoms of nasal obstruction, discharge and polyps. Correct identification of the fungus remains essential for appropriate treatment.

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Section: Resultssupporting

confidence: 62%

Section: Resultsmentioning

confidence: 99%

Study on Chronic Rhinosinusitis: A Clinico-Mycological Perspective in a Tertiary Care Centre

Syiemlieh¹,

Mariraj²

2020

Int.J.Curr.Microbiol.App.Sci

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“…However, systematic study of the dermatophytes began with the classification of the mycotic agents by Sabouraud into 4 groups— Achorion , Epidermophyton , Trichophyton and Microsporum . He also classified the spores of various aetiologic agents causing tinea capitis as ectothrix, endothrix, neoendothrix and microscopic 17,19,20 …”

Section: Historical Backgroundmentioning

confidence: 99%

“…He also classified the spores of various aetiologic agents causing tinea capitis as ectothrix, endothrix, neoendothrix and microscopic. 17,19,20 Several important discoveries on the taxonomy of dermatophytes were made in the second half of the 19th century. Earlier (1920s), the sexual phases of certain dermatophytes were recognised by Nannizzi who named the sexual form of M. gypseum as Gymnoascus gypseum.…”

mentioning

confidence: 99%

Superficial mycoses, a matter of concern: Global and Indian scenario‐an updated analysis

Sharma

Nonzom

2021

Mycoses

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Superficial mycoses are the fungal infections restricted to the outermost non-living layers of the skin and its appendages viz., hair and nails. Their prevalence rate has been reported to be 20%-25% 1 and vary with respect to occupational groups, gender, age group, etc. These infections are more common in tropical as well as subtropical countries where heat, humidity and other favourable conditions aid in their acquisition and maintenance. Although superficial mycotic infections are usually limited to the skin and mucous membranes, these infections are hardly life-threatening but they have importance because of their worldwide distribution, morbidity and transmission from one person/animal to another.Over the last decades, it has been observed that an increasing number of non-dermatophytic fungi, like, Alternaria, Aspergillus, Chaetomium, Curvularia, Fusarium, Penicillium, Scopulariopsis and Trichosporon, have also emerged as causal agents of superficial mycoses in humans, producing almost clinically similar lesions as caused by dermatophytes. 2,3 Although both dermatophytes and non-dermatophytes have been known to cause superficial mycoses all over the world, their incidence, distribution, prevalence, epidemiology, clinical manifestation and target hosts may vary from region to region. 4,5 In this review, more emphasis has been provided on information related to skin and hair infections.

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“…Since the past two decades, fungi are increasingly recognized as a significant cause of morbidity and mortality among the patients [1] because of the wider use of broad-spectrum antibiotics, immunosuppressive therapy, cancer chemotherapy, increased incidence of immunodeficiency diseases and increased use of intensive care interventions.…”

Section: Introductionmentioning

confidence: 99%

Fungal rhinosinusitis: A clinicomycological perspective

Krishnan

Agatha

Selvi

2015

Indian Journal of Medical Microbiology

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Historical Introduction: Evolution of Knowledge of the Fungi and Mycoses from Hippocrates to the Twenty-First Century

Cited by 4 publications

References 153 publications

Study on Chronic Rhinosinusitis: A Clinico-Mycological Perspective in a Tertiary Care Centre

Study on Chronic Rhinosinusitis: A Clinico-Mycological Perspective in a Tertiary Care Centre

Superficial mycoses, a matter of concern: Global and Indian scenario‐an updated analysis

Fungal rhinosinusitis: A clinicomycological perspective

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