History Taking as a Diagnostic Tool in Children With Chronic Cough

Kantar, Ahmad; Marchant, Julie M.; Song, Woo-Jung; Shields, Michael; Chatziparasidis, Grigorios; Zacharasiewicz, Angela; Moeller, Alexander; Chang, Anne B.

doi:10.3389/fped.2022.850912

Cited by 8 publications

(4 citation statements)

References 74 publications

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“…It is a major source of concern for parents in the pediatric population. (5) Chronic cough in children differs from chronic cough in adults in terms of etiology and management, as it may be a symptom of an underlying disease (6). Young children are likely to cough more as they are more likely to have infections.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Chronic Cough Etiologies in Children

Topal¹

2023

Türkiye Çocuk Hast Derg

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Objective: Cough is one of the leading causes of hospitalization in children worldwide. It should be considered important because it can be a symptom of various serious diseases and affects the quality of life of the child. A differential diagnosis should be performed on all children with a chronic cough. This study aimed to determine the etiologies in patients evaluated for chronic cough. Material and Methods: The study included patients admitted to the pediatric immunology and allergy outpatient clinic, with the complaint of chronic cough between the ages of 0–18 years. Clinical and demographic characteristics of patients were recorded. Results: This study included 323 patients between the ages of 0-18years. The median age of the patients was 7 (interquartile range: 5-9.7) years. One hundred and forty five (45%) of the patients were female. One hundred seventy-nine (55.4%) patients had a family history of atopic diseases such as asthma and/or allergic rhinitis. The presence of aeroallergen sensitivity was demonstrated in 127 patients. One hundred and forty-four (44.6%) patients were diagnosed with asthma, 75 (23.2%) patients with wheezing, 54 (16.7%) patients with post-infectious cough, 43 (13.3%) patients with postnasal drip syndrome, 4 (1.2%) patients with gastroesophageal reflux, 2 (0.6%) patients with foreign body aspiration, and 1 (0.3%) patient with psychogenic cough. Moreover, two patients with asthma, and one patient with wheezing had reflux symptoms in addition to the diagnosis of asthma and wheezing. One patient was found to have a partial IgA deficiency, and 18 patients had hypogammaglobulinemia. Immunoglobulin replacement therapy was initiated for a patient with hypogammaglobulinemia. Of the 219 patients diagnosed with asthma or wheezing, 144 had an atopic disease in the family (p<0.001). It was found that one hundred and eighty-five patients (57.3%) had domestic smoke exposure. Furthermore, smoke exposure was observed in 58 (77.3%) of 75 patients under the age of 6 years who were followed up with the diagnosis of wheezing (p= 0.010). Conclusion: In our study, asthma, which is one of the most common causes of chronic cough in the literature, was found to be the most common cause. For a correct approach when making a differential diagnosis in pediatric patients presenting with chronic cough, the patient’s history, physical examination, laboratory tests, and risk factors should be evaluated as a whole with systematic evaluation.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Chronic Cough Etiologies in Children

Topal¹

2023

Türkiye Çocuk Hast Derg

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“…This study was performed using a modified Delphi method by de Kleuver et al ( 11 , 12 ). To review the primary literature, eight fields of chronic cough in children were considered: the composition of chronic cough etiology in Chinese children using multicenter studies ( 10 ); recommendations for the diagnosis and treatment of children with rhinosinusitis ( 13 ); guidelines for the diagnosis and treatment of chronic cough in Chinese children ( 1 ); expert consensus on the diagnosis and treatment of chronic wet cough in Chinese children ( 14 ); management pathways or algorithms for use in children with chronic cough (CVD) ( 15 ); guidelines for the diagnosis and treatment of chronic cough in adults and children ( 6 ); guidelines and expert consensus on chronic cough in children ( 16 ); and the use of medical history as a diagnostic tool for chronic cough in children ( 17 ). To summarize the above literature, we described the process of diagnosis and treatment of chronic cough in children, combined with the current pediatric situation in primary Chinese hospitals.…”

Section: Manuscript Formattingmentioning

confidence: 99%

Process of diagnosis and treatment of chronic cough in children at primary hospitals

Shen

Zhang

et al. 2022

Front. Pediatr.

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ObjectiveThis study aimed to establish a process for the diagnosis and treatment of chronic cough in children suitable at primary hospitals and improve the treatment efficacy rate and improve health economic indicators.MethodsChildren who visited the Department of Pediatrics, Affiliated Zhou Pu Hospital of the Shanghai Health Medical College from January to December 2021 were randomly assigned to the intervention group (n = 206), in which the diagnosis and treatment process proposed here was applied, and a control group (n = 211) that did not follow the intervention pathway and followed a pathway with the doctors usual practice based on his/her previous experience. Patients were followed up and data were collected at weeks 0 (time of enrollment), 2, 4, 8, and 12 to evaluate the efficacy rate and clinical value.Results(1) No significant differences were detected between the two groups in baseline characteristics, including gender, age, duration of cough (weeks), history of allergy in children and parents, and smoking of family members living in the same household (p > 0.05); (2) During the follow-up, all cough symptom scores of the intervention group were lower than the control group. Additionally, at week 12, the treatment efficacy rate of the intervention group (91.70%) was significantly higher than the control group (69.20%) (p < 0.05); (3) The quality of life of children in both groups at week 12 was improved compared to the first visit. However, the total score of the intervention group was significantly higher than the control group (p < 0.05); (4) At week 12, the referral rate was significantly lower in the intervention group (11.17%) than in the control group (21.33%); (5) The intervention group was better than the control group for the mean monthly medication costs, number of days on errors in childhood, and number of days mistakenly worked by family members at week 12 (p < 0.05).ConclusionThe current process of diagnosis and treatment of chronic cough in children at primary hospitals can improve the effective diagnosis and treatment rate, the quality of life, and other parameters, with good effectiveness and feasibility.

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“…Chronic cough (defined as a cough lasting for >4 and 8 weeks in children and adults, respectively) is also a prevalent symptom of several underlying respiratory and non-respiratory conditions [2]. Chronic cough in children varies from that in adults in terms of cause and management [1,3]. Bronchiectasis is a spectrum of suppurative lung diseases characterised by persistent wet/sputum-productive cough and airway dilatation, with a substantial burden on patients and healthcare expenditure [4,5].…”

Section: Introductionmentioning

confidence: 99%

Cough in non-cystic fibrosis bronchiectasis

Kantar,

Song,

Bush

et al. 2024

ERJ Open Res

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Non-cystic fibrosis bronchiectasis (NCFBE) belongs to the spectrum of chronic suppurative lung diseases and is characterised by persistent wet/sputum-productive cough and airway dilatation. Morphological and structural changes in the airways lead to changes in airflow, impair breathing-induced mucus transport and sliding, and reduce the shear forces of cough. Moreover, mucus hyperviscosity contributes to compromised ciliary activity and the pathogenesis of the disease. This review highlights the role of cough in NCFBE, especially with respect to mucus clearance.Cough is the principal backup mechanism when mucus clearance is impaired due to either or both reduced function of cilia- and breathing-induced mucus transport, as well as abnormal mucus. The efficiency of cough in overcoming the cohesive and adhesive properties of mucus is determined by both the forces applied to mucus by airflow and the mucus-airway surface properties.In NCFBE, mucus hyperviscosity contributes to impaired mucus clearance and confers to disease pathogenesis; therefore, it may be a therapeutic target. The primary objectives of physiotherapy regimens in NCFBE are mucus hydration and the establishment of an optimal expiratory airflow velocity, which exerts shearing forces on the mucus located on the airway surface. Modifying the rheological properties of mucus and enhancing its transport whenever possible (by breathing manoeuvres, ciliary activity, and cough) represent prime goals in preventing disease progression and indeed reversing bronchiectasis in the early stages of the disease, as well as preventing pulmonary exacerbations.

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History Taking as a Diagnostic Tool in Children With Chronic Cough

Cited by 8 publications

References 74 publications

Evaluation of Chronic Cough Etiologies in Children

Evaluation of Chronic Cough Etiologies in Children

Process of diagnosis and treatment of chronic cough in children at primary hospitals

Cough in non-cystic fibrosis bronchiectasis

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