HIV prevalence, knowledge and self-perceived risk of HIV infection among tuberculosis patients in Serbia

Stošić, Maja; Simić, Danijela; Babić, Dragan; Ristic, Lidija; Kuruc, Vesna

doi:10.21101/cejph.a4950

Cited by 3 publications

(3 citation statements)

References 16 publications

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“…Low levels of suspicion of clinicians as well as difficulties in obtaining adequate samples for confirmation are also reported as a challenge in EPTB diagnosis [21]. In addition, some of the reasons for higher proportion of PTB in Serbia compared with EU/EEA countries could be due to low HIV prevalence in Serbia [22] and to the dominant proportion of men among TB patients as there is evidence that the incidence of EPTB is likely to be higher among women than men [23].…”

Section: Discussionmentioning

confidence: 99%

Trends in tuberculosis notification and mortality and factors associated with treatment outcomes in Serbia, 2005 to 2015

et al. 2020

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Background: Previously a country with medium tuberculosis (TB) burden, Serbia almost reached a low TB burden during the period 2005 to 2015. Aim: The aim of this study was to analyse the trends in notification rates and treatment success rates as well as to identify predictors of treatment outcomes. Methods: We performed a trend analysis and logistic regression analysis of 17,441 TB cases registered from 2005 to 2015 in all health facilities in Serbia, to identify predictors of treatment success, loss to follow-up and mortality. Results: From 2005 to 2015, TB notification rate and mortality in Serbia decreased but treatment success remained below the global target. Loss to follow-up was associated with retreatment (odds ratio (OR) = 2.38; 95% confidence interval (CI): 2.08-2.77),

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Section: Discussionmentioning

confidence: 99%

Trends in tuberculosis notification and mortality and factors associated with treatment outcomes in Serbia, 2005 to 2015

et al. 2020

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“…These proportions correspond to EU/EEA surveillance data [2], less than proportions presented in WHO standards and benchmarks for childhood TB (5-15%) for middleincome countries where Serbia belongs [19], reflecting some improvements in case detection. However, it is reasonable to assume that country is still facing challenges in TB control in child and adolescent population such as: sub-registration [20], under diagnosis and misdiagnosis due to difficulties in obtaining adequate samples, especially in children aged <5 years, as illustrated by a recent review where between 1% and 23% of pneumonia cases also had TB [23,24].…”

Section: Discussionmentioning

confidence: 99%

“…The reason might be the fact that patients with infectious forms of PTB and comorbidities are likely to be hospitalized and under direct supervision of the health worker, unlikely to be lost to follow up. On the other hand, EPTB forms of the disease in children are often severe, towards unfavorable treatment outcomes [23,24].…”

Section: Discussionmentioning

confidence: 99%

Tuberculosis and associated risk factors among children and adolescent population in Serbia: 12 year’s retrospective study

Stošić

Sagić

Simić

et al. 2021

J Infect Dev Ctries

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Introduction: Recognition and epidemiological control of childhood and adolescent tuberculosis (TB) is essential to achieve effective control of TB in general as it presents high risk for transmission in the community. The aim of the study is to provide a descriptive and analytic overview of the trends in childhood and adolescent TB notifications and treatment outcomes and to identify factors associated with treatment success in a twelve-year period in Serbia. Methodology: We performed a retrospective trend analysis and analysis of treatment outcomes of 596 child and adolescent TB cases notified in Serbia in the period 2005–2016 from all health facilities, as well as logistic regression analysis to identify predictors of treatment success. Results: Factors independently associated with treatment success were: new TB (OR=2.60; 95% CI: 1.45–3.74), male sex (OR=2.55; 95% CI: 2.09–3.00), pulmonary TB (OR=3.34; 95% CI: 2.34–4.34), comorbidities (OR=2.58; 95% CI: 2.24–2.91), age below 5 years (OR=0.37; 95% CI: 0.32–0.43), and social vulnerability (OR=0.40; 95% CI: 0.34–0.46). Conclusions: In order to improve TB treatment outcomes among children and adolescent population in Serbia, it is important to focus on female, age group 5-18, EPTB, retreatment cases and socially vulnerable groups.

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Analysis of the multi-drug resistant tuberculosis treatment outcomes: Experience from the special hospital for pulmonary diseases "Ozren" - Sokobanja

Antonijević,

Stošić

2024

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Multidrug-resistant tuberculosis (MDR TB) is currently considered to be the most significant and dangerous obstacle to the TB elimination, and the work on preventing this form of disease is considered as a major contribution to human health and resource management. The purpose of the article is to analyse treatment outcomes in patients treated for multiresistant tuberculosis at the Special Hospital for Pulmonary Diseases "Ozren" - Sokobanja in the period from 2009 to 2019 and identify factors associated with treatment outcomes. We performed a retrospective analysis of the treatment outcomes in all (n=89) cases of MDR TB treated over the period from 2009-2019 at the Special Hospital for Pulmonary Diseases Ozren - Sokobanja. Descriptive statistical analysis of all available MDR TB characteristics was used. Logistic regression analysis was used to identify factors associated with successful treatment (treatment outcomes "cured" and "treatment completed") and mortality. Patient mortality was statistically significantly associated with undernutrition (OR = 5.55; 95% CI: 1.39-20.00), alcohol consumption (OR = 4.54; 95% CI: 1.22-10.67), bilateral cavitary lesions (OR = 16.67; 95% CI: 3.03-100.00), multiple prior treatment episodes (p<0.001), longer time to diagnosis (p<0.001), higher average number of hospitalizations and previous treatment episodes (p<0.001), and the following comorbidities: pulmonary (OR = 14.29; 95% CI: 2.70-100.00), cardiovascular diseases (OR = 7.14; 95% CI: 1.79-25.00), diabetes (OR = 5.88; 95% CI: 1.39-25.00) and malignant diseases (OR = 12.50; 95% CI: 1.85-100.00). The success of MDR TB treatment is very good. To maintain and further improve this success, it is necessary to focus interventions on resolving social issues and comorbidities among patients from risk groups associated with poor treatment outcomes, as well as on education of health professionals related to suspicion of TB, its recognition and referral to specialized institutions for MDR TB diagnostics and treatment.

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HIV prevalence, knowledge and self-perceived risk of HIV infection among tuberculosis patients in Serbia

Cited by 3 publications

References 16 publications

Trends in tuberculosis notification and mortality and factors associated with treatment outcomes in Serbia, 2005 to 2015

Trends in tuberculosis notification and mortality and factors associated with treatment outcomes in Serbia, 2005 to 2015

Tuberculosis and associated risk factors among children and adolescent population in Serbia: 12 year’s retrospective study

Analysis of the multi-drug resistant tuberculosis treatment outcomes: Experience from the special hospital for pulmonary diseases "Ozren" - Sokobanja

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