Homeostasis and Aging. Slow-Fast Dynamics of Senescence and Death

Novoseltsev, V. N.; Novoseltseva, Janna; Boyko, Sergei I.; Yashin, Anatoli I.

doi:10.1016/s1474-6670(17)35490-3

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…Methodological approaches based on the use of various modifications of the Gompertz function are applicable in the analysis of the survival rate of laboratory animals and dairy cows [14][15][16][17][18][19][20][21][22][23][24]. The assumption is substantiated that in order to reduce the loss of productive animals from numerous polyetiological diseases (including so-called "productivity diseases", i.e., diseases of the udder, reproductive organs, legs, etc.…”

Section: Introductionmentioning

confidence: 99%

In Silico Predictions on the Productive Life Span and Theory of Its Developmental Origin in Dairy Cows

Kharitonov¹,

Cherepanov²,

Остренко³

2022

Animals

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Animal welfare includes health but also concerns the need for natural factors that contribute to the increase in viability. Therefore, quantitative parameters are necessary to predict the risks of early culling of cows. In the study of the age dynamics of the disposal rate (culling for sum of reasons + death) in dairy cow populations, it was found that the average productive life span can be predicted by the value of the reciprocal culling/death rate (reciprocal value of Gompertz function) at the first lactation. This means that this potential of viability is formed during the developmental periods preceding the onset of lactation activity. Therefore, taking into account current data in the field of developmental biology, it can be assumed that the structural prerequisites for viability potential are laid down during prenatal development and in the early periods of postnatal life. To prevent unfavorable deviations in these processes due to negative welfare effects, it is advisable to monitor the physiological status of mothers and young animals using biosensors and Big Data systems.

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