Homogeneous nucleation in cooling crystallization

Abstract

NILLSBN'S cyuat ion has been applied for cooling crystallization of KC'I from watcry soltitioils. In tho calculations activities are used instead of concentratioris, the temperature and coricontration deperidencc of both the activity and diffusion cocfficients are COIIsidered. It is found that a) the interfacial tension betwocri the crystal and its saturated solution is < 2.5 wg/crn2, which is less by t w o orders of magnitude than that of between crystal and vacuum; b) homogeneous nucleation can take place even at very small supersaturations (In 8 < < 0.01), which is unusual 111 precipitation.

Solubility and Crystallization of Glucosamine Hydrochloride in Water with the Presence of Additives

“…This work can provide an important reference for the crystallization and preparation of GAH. The effects of GAH on crystal morphology, particle size, and yield in the presence of HCl, NaCl, and KCl were studied by cooling crystallization, and the products were characterized by powder X-ray diffraction, polarizing microscopy, and crystal size analyzer [15].…”