Hormonal therapy for ovarian dysfunctions in high-productive cows

Abstract

The analysis was made of culling data in the farm of the Udmurt Republic. As a result, it was found that the animals are eliminated due to gynecological and limb diseases. They make up 19–24 % and 18–31 % respectively. Analyzing the results of gynecological clinical examination of cows, we found a predominance of ovarian diseases 32–36 %, as well as endometritis 28–30 %. The ovarian dysfunction progresses mostly. This can be attributed to an increase in the productivity of cows in the Udmurt Republic over the past 5 years from 5601 to 6250 kg per 1 cow. In connection with an increase in the incidence of ovaries, the calf yield per 100 cows decreases from 88 to 85 %. Causes of ovarian disease can be diseases of the birth and postpartum period. For the treatment of ovarian hypofunction, 3 schemes were used for anestral and reactive reproductive cycles. Often, the cause of ovarian hypofunction is uterine pathology; drugs that have a therapeutic effect on the uterus are included in the scheme.

Reproductive disorders of cows in several villages of Kedamean district, Gresik regency, East Java, Indonesia in 2023

“…Several pharmacological substances and their application techniques had been reported to be effective in suppressing hypofunctional estrus in cows. The combination of Metrostim (the active substance is carbacholine) had a restoring effect on the myometrium, and Surfagon, a synthetic analog of Gonadotropin-Releasing Hormone, had a gonadotropic effect (Khamitova et al, 2020). Treatment of bovine OHF with intraovarian administration of autologous platelet-rich plasma, which was rich in growth factors, chemokines, and cytokines, had been reported to stimulate follicle growth and steroidogenesis.…”