Host–microbial co-evolution in periodontitis associated with Aggregatibacter actinomycetemcomitans infection

Draft Genome Sequence of Neisseria mucosa Strain HSUH001, Isolated from an Aggressive Periodontal Lesion

“…The sample was spread onto the agar medium and incubated at 37°C for several days in an incubator supplemented with 5% CO 2 . The predominant colony type was observed to be white, small, and smooth ( 5 ). One of the colonies was repeatedly streaked onto the agar medium for isolation and was stored at −80°C.…”

Oral Biosciences: The annual review 2014

“…Not all bacteria in the biofilm are equally pathogenic, and Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis show particularly strong associations with periodontitis [2]. On the basis of current research on the interaction of A. actinomycetemcomitans with the host immune system, Nagasawa and colleagues in their review article summarized A. actinomycetemcomitans-associated periodontitis as a model for symbiosis and dysbiosis in periodontal disease [3]. They proposed that elucidation of host-microbial coevolution may enable increased understanding of the dysbiosis that is caused by A. actinomycetemcomitans, and discussed strategies for developing diagnostic and treatment methods for A. actinomycetemcomitans-associated periodontitis.…”