Hot Topic: [Recent Concepts in Nutrition (Guest Editor: Ram B Singh)]

Abstract

's earlier research had focused on the metabolism of vitamins, particularly retinol, ascorbic acid and thiamin. He had studied the relationship of these vitamins with malignant diseases. Highlights of his work include: a) establishing a link between biochemical evidence of secondary deficiency of vitamin A due to its metabolic unavailability and cancers of the epithelial cell origin, such as bronchus, lung and endometrium in humans [1-5]; b) determining an association between breast cancer, especially with skeletal metastases and ascorbic acid deficiency as well as providing mechanistic beneficial effects of ascorbic acid supplement to these patients [6,7]; and