How to design high quality acupuncture trials—a consensus informed by evidence

Zhang, Yuqing; Jiao, Ruimin; Witt, Claudia M.; Lao, Lixing; Liu, Jianping; Thabane, Lehana; Sherman, Karen J.; Cummings, Mike; Richards, Dawn P.; Kim, Eun-Kyung Anna; Lee, Myeong Soo; Wechsler, Michael E.; Brinkhaus, Benno; Mao, Jun J.; Smith, Caroline; Gang, Wei-Juan; Liu, Baoyan; Liu, Zhishun; Liu, Yan; Zheng, Hui; Wu, Jiani; Carrasco‐Labra, Alonso; Bhandari, Mohit; Devereaux, P.J.; Jing, Xiang-Hong; Guyatt, Gordon

doi:10.1136/bmj-2021-067476

Cited by 37 publications

(29 citation statements)

References 72 publications

(70 reference statements)

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“…First, skepticism remains about the effectiveness of acupuncture on cardiopathies, limited by many problems in designing and implementing existing trials. This is a common challenge in RCTs of acupuncture, and fortunately, scholars have focused on this issue and developed guidance for designing high-quality clinical trials, covering complete methodological recommendations ( 70 ). Therefore, future clinical studies about acupuncture on cardiopathies are expected to provide high-quality evidence for clinical practice and Medicare reimbursement decisions with rigorous methodological design.…”

Section: Discussionmentioning

confidence: 99%

The application of acupuncture in cardiopathy: A bibliometric analysis based on Web of Science across ten recent years

Yin

Ling

et al. 2022

Front. Cardiovasc. Med.

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BackgroundWith high morbidity and mortality, cardiopathy is a major component of cardiovascular disease, causing a huge burden of disease to public health worldwide. In recent years, research on acupuncture treatment of cardiopathies has been increasing. However, no bibliometric analysis has been conducted to systematically describe the research progress and hotspots in this field. Therefore, this study aimed to conduct a bibliometric analysis of the relevant literature to explore the current status and future development of acupuncture for cardiopathies.MethodsThe Web of Science (WoS) Core Collection Database was searched for literature related to acupuncture therapies for cardiopathies from 2011 to 2021. Using CiteSpace 5.8 R3, cooperation network diagrams of authors, institutions, countries and journals, keyword co-occurrences, and clustering were performed and analyzed.ResultsA total of 321 studies were included. Overall, the number of annual publications increased yearly. These publications came from 31 countries or regions, of which China and the United States made the greatest contributions. In total, 333 authors from 258 institutions participated in this field, and Beijing University of Chinese Medicine and Professor Fanrong Liang were the most published institution and author, respectively. Evidence-based Complementary and Alternative Medicine published the largest number of articles, and CIRCULATION was the most commonly cited journal. Based on co-occurrences and cluster analysis of 257 keywords, three research frontiers and hotspots were identified: acupuncture for blood pressure regulation, acupuncture for coronary heart disease, and acupuncture for regulation of heart rate. In these three research frontiers, the rostral ventrolateral medulla (RVLM) and autonomic nervous system (ANS) are the most popular mechanisms.ConclusionA stable development trend has formed in this field. Further research should focus on the role of acupuncture therapies in the treatment of hypertension or hypertensive heart disease, coronary heart disease, and arrhythmia based on the mechanisms related to the RVLM and ANS.

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Section: Discussionmentioning

confidence: 99%

The application of acupuncture in cardiopathy: A bibliometric analysis based on Web of Science across ten recent years

Yin

Ling

et al. 2022

Front. Cardiovasc. Med.

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“…For example, studies have been conducted on optimal stimulation intensity and number or frequency of treatment sessions 5) . A recent study published in British Medical Journal 6) emphasised the design of highquality acupuncture studies, and proposed the formation of an expert committee to define the optimal strategy for the details of acupuncture as a consideration. Welcome to the opportunity to have this topic on stage.…”

Section: Song-yi Kimmentioning

confidence: 99%

Do Different Numbers of Acupuncture Treatments Have Different Effects on Migraine Symptoms?: Lessons Learned from Recent Research Published in Acupuncture in Medicine

Kim

2022

Korean J Acupunct

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“…Acupuncture has been practiced for more than 2000 years and has acquired abundant experience in poststroke rehabilitation [ 18 , 19 ]. With the advantage of effectiveness, acupuncture has been applied in more than 183 countries and areas all over the world [ 20 , 21 ]. Meanwhile, the safety of acupuncture has been approved by quantitative evidence.…”

Section: Introductionmentioning

confidence: 99%

Cerebral Blood Flow Velocity Modulation and Clinical Efficacy of Acupuncture for Posterior Circulation Infarction Vertigo: A Systematic Review and Meta-Analysis

Zhao

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Background. Vertigo is a cardinal symptom of posterior circulation infarction (POCI). Acupuncture is demonstrated to have a beneficial effect on posterior circulation infarction vertigo (PCIV). However, the mechanism of acupuncture therapy is not clarified. This study aims to assess the cerebral blood flow velocity modulation and clinical efficacy of acupuncture for PCIV patients. Methods. We conducted this systematic review for clinical randomized controlled trials (RCTs) regarding acupuncture on PCIV. The study duration was from September 2020 to September 2021. We searched the PubMed, EMBASE, Cochrane Library, Web of Science, Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP. The publication date was set from inception to August 31, 2020. Based on the inclusion and exclusion criteria, two researchers independently screened literature and extracted data including basic study information, intervention details, outcome details, and adverse events. Outcome measures included the blood flow velocities of vertebrobasilar arteries and the Clinical Effective Rate of posterior circulation infarction vertigo. Pooled data were presented as standardized mean differences (SMDs) and relative risks (RR), with 95% confidence intervals (CIs). The meta-analysis was conducted using Review Manager software version 5.3.0. Results. A total of 20 eligible RCTs (1541 participants) were included in this review, which compared acupuncture therapy (1 RCT) or acupuncture combined with pharmaceutical therapy (19 RCTs) to pharmaceutical therapy in patients with posterior circulation infarction vertigo. 7 studies assessed the blood flow velocities of the basilar artery examined by Transcranial Doppler (TCD), 8 studies assessed the bilateral vertebral arteries, and 13 studies evaluated the Clinical Effective Rate of posterior circulation infarction vertigo. Meta-analysis results showed that blood flow velocities of the basilar artery (SMD = 0.58, 95% CI = 0.40–0.76; P < 0.05 ), left vertebral artery (SMD = 0.48, 95% CI = 0.22–0.73; P < 0.05 ), and right vertebral artery (SMD = 0.44, 95% CI = 0.19–0.69; P < 0.05 ) were significantly higher in the acupuncture group compared with the control group. Clinical Effective Rate (RR = 1.22, 95% CI = 1.15–1.29; P = 0.792 ) was significantly better in the acupuncture group compared with the control group. Conclusions. This study shows that acupuncture therapy is useful in improving the blood flow velocity of vertebrobasilar arteries and Clinical Effective Rate in patients with posterior circulation infarction vertigo. However, double-blind, sham-controlled trials with large sample sizes are required to support our conclusions.

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How to design high quality acupuncture trials—a consensus informed by evidence

Cited by 37 publications

References 72 publications

The application of acupuncture in cardiopathy: A bibliometric analysis based on Web of Science across ten recent years

The application of acupuncture in cardiopathy: A bibliometric analysis based on Web of Science across ten recent years

Do Different Numbers of Acupuncture Treatments Have Different Effects on Migraine Symptoms?: Lessons Learned from Recent Research Published in Acupuncture in Medicine

Cerebral Blood Flow Velocity Modulation and Clinical Efficacy of Acupuncture for Posterior Circulation Infarction Vertigo: A Systematic Review and Meta-Analysis

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