How to proceed in the case of a tumour thrombus in the inferior vena cava with renal cell carcinoma

Certík, B; Třeška, Vladislav; Moláček, Jiří; Sulc, R

doi:10.1016/j.crvasa.2015.02.015

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…Potentially curative treatment includes nephrectomy and thrombectomy, invasive cardiopulmonary bypass (CPB), and deep hypothermic circulatory arrest (DHCA) [ 13 , 16 ]. Although CPB with DHCA is relatively safe, the risk of platelet dysfunction, coagulopathy, hypothermia, and intensive multi-disciplinary care may be challenging [ 1 , 14 ]. The radical surgery is associated with 30–35% morbidity [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

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Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus

Bełdzińska¹,

Gądek²,

Rutkowski³

2022

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Renal cell carcinoma (RCC) constitutes about 3% of all malignant neoplasms in adults. Clear cell carcinoma is the most frequent type, accounting for about 65% of cases. It tends to invade the veins and form tumour thrombi in inferior vena cava (IVC-TT), occasionally reaching the right atrium. Nephrectomy and thrombectomy are standard therapeutic procedures performed in RCC-IVC-TT. Despite proven effectiveness of surgery, this entity in IVC-TT is associated with poor outcome. The role of palliative radiotherapy in this entity is undetermined. We present a case of a 43-year-old female patient after right-sided nephrectomy due to advanced RCC which invaded the IVC, hepatic veins, and right atrium. The patient has been treated with postoperative, hypofractionated radiotherapy on the residual disease.

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Section: Discussionmentioning

confidence: 99%

“…Renal cell carcinoma (RCC) constitutes about 3% of all malignant neoplasms in adults [ 1 ]. The most common histologic type of RCC, about 65% of cases, is clear cell carcinoma [ 1 ]. Renal cell carcinoma is asymptomatic in most cases.…”

Section: Introductionmentioning

confidence: 99%

Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus

Bełdzińska¹,

Gądek²,

Rutkowski³

2022

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Renal cell carcinoma with tumor thrombus extending in the right atrium

Žemla¹,

Vidlář²,

Šantavý³

et al. 2018

Urolog. pro Praxi

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Karcinom ledviny je nejčastějším primárním nádorem ledviny a Česká republika má z celého světa jeho nejvyšší incidenci. V do bě diagnózy je u 4-10 % pacientů zaznamenán nádorový trombus prorůstající do dolní duté žíly. Přesto je karcinom ledviny ve většině případů klinicky němý nebo se může projevovat atypickými příznaky. V prezentovaném případu dojde k diagnóze karcinomu ledviny s nádorovým trombem prorůstajícím do pravé srdeční síně náhodně až na základě náhle vzniklé dušnosti. Za spolupráce s kardiochirurgy naše pacientka podstoupila pravostrannou radikální nefrektomii s kavotomií a exstirpací nádorového trombu z pravé srdeční síně. Součástí výkonu bylo zavedení mimotělního oběhu s hlubokou hypotermií. I přes pokročilé stadium nádorového trombu operace proběhla úspěšně a pacientova prognóza je srovnatelná s pacienty, u kterých je nádorový trombus omezen pouze na renální žílu.Klíčová slova: karcinom ledviny, nádorový trombus. Renal cell carcinoma with tumor thrombus extending in the right atriumRenal cell carcinoma is the most common primary kidney tumor. Czech Republic has the highest incidence of this type of tumor in the world. The occurrence of a tumor thrombus in the inferior vena cava is recorded in 4 % up to 10 % of patients at the time of diagnosis. Renal cell carcinoma is in the most cases clinically mute or it may appear by atypical symptoms. In our case, the diagnosis of the renal cell carcinoma with a tumor thrombus extending in the right atrium was incidental, based on the sudden stuffiness. In collaboration with cardiac surgeons, the patient underwent a radical nephrectomy with cavotomy and exstirpation of the tumor thrombus protruding into right atrium through visual control. Despite the advanced stage of the tumor thrombus, the surgery was successful and there is similar prognosis as if the tumor thrombus was restricted to the renal vein.

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How to proceed in the case of a tumour thrombus in the inferior vena cava with renal cell carcinoma

Cited by 2 publications

References 6 publications

Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus

Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus

Renal cell carcinoma with tumor thrombus extending in the right atrium

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