HPLC Profile and Different Pathways Involved in Achillea odorata-Induced Gastric Emptying and Intestinal Transit Delay

Abstract

Medicinal plants have been used historically to treat a variety of human ailments in traditional methods. As gastrointestinal disorders have the potential to have a major negative impact on health and even result in death all over the world, there is increasing interest in discovering novel compounds that can effectively treat these disorders. 1 Research from the previous year concentrated on treating and preventing digestive tract disorders with traditional medicine. 2 The digestive system fulfils several vital roles that allow the body to get the nutrients it needs, such as vitamins, minerals, water, proteins, carbohydrates and electrolytes. Numerous neurotransmitters and mediators are involved in the complex process of controlling GE and IT. 3 Any disruption to those mechanisms leads to a variety of ailments, such as diarrhoea and constipation. Certain pathophysiological complications of the gastrointestinal tract are known to be influenced by dysfunction of gastrointestinal motility. 4