Previously, rapid disease detection and prevention was difficult. This is because disease modeling and prediction was dependent on a manually obtained dataset that includes use of survey. With the increased use of social media platforms like Twitter, Facebook, Instagram, etc., data mining and sentiment analysis can help avoid diseases. Sentiment analysis is a powerful tool for analyzing people's perceptions, emotions, value assessments, attitudes, and feelings as expressed in texts. The purpose of this research is to use machine learning techniques to classify and predict the spatial distribution of positive and negative sentiments of Covid-19 pandemic. This study research has employed machine learning to classify spatial distribution of Covid-19 twitter sentiments as positive or negative. The data for this study were geo-tagged tweets concerning COVID-19 which were live streamed using streamR package. The key terms used for streaming the data were: Corona, Covid-19, sanitizer, virus, lockdown, quarantine, and social distance. The classification used Naive Bayes algorithms with ngram approaches. N-Gram model is a probabilistic language model used to predict next item in a sequence in the form (n − 1) order Markov. It relies on the Markov assumption-the probability of a word depends only on the previous word without looking too far into the past. The steps followed in this research include: cleaning and preprocessing the data, text tokenization using n-gram i.e. 1-gram, 2-gram, and 3-gram, tweets were converted or weighted into a matrix of numeric vectors using Term Frequency Inverse-Document. Also, data were divided 80:20 between train and test data. A confusion matrix was utilized to evaluate the classification accuracy, precision, and recall performance of the various algorithms tested. Prediction was done using the best performing Naive Bayes algorithm. The results of this research showed that under Multinomial Naive Bayes, unigram accuracy was 92.02%, bigram accuracy was 97.37%, and trigram accu-