Abstract:OBJECTIVES: Decisions about the use of new medical technologies based on estimates of the average cost-effectiveness across a potentially heterogeneous population runs the risk of foregoing net health benefits(NHB) for sub-groups of the population. We propose a general framework within which to assess betweenpatient heterogeneity and its role in cost-effectiveness subgroup analysis(CESA), complementing this with a practical application. METHODS: We first describe how to extend methods for cost-effectiveness an… Show more
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