Human growth factor-mediated signalling through lipid rafts regulates stem cell proliferation, development and survival of
Schistosoma mansoni
Shradha Maharjan,
Ruth S. Kirk,
Scott P. Lawton
et al.
Abstract:Although the mechanisms by which schistosomes grow and develop in humans are poorly defined, their unique outer tegument layer, which interfaces with host blood, is considered vital to homeostasis of the parasite. Here, we investigated the importance of tegument lipid rafts to the biology of
Schistosoma mansoni
in the context of host–parasite interactions. We demonstrate the temporal clustering of lipid rafts in response to human epidermal growth factor (EGF) during early somule develop… Show more
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