2021
DOI: 10.1096/fasebj.2021.35.s1.03969
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Human Molar Size Variation: Wisdom Teeth Just Don't Care?

Abstract: The inhibitory cascade model (ICM) is a tenet of mammalian molar morphogenesis that predicts that a larger developing first molar (M1) results in a smaller and later‐forming adjacent second (M2) and third (M3) molar. Recently, we have shown that late‐developing M3s are also at higher risk of impaction, a common dental health concern worldwide. The mechanisms delaying M3 onset time are unclear.Here we tested the hypothesis that M1 crown size predicts M3 developmental timing and M3 eruption, based on a sample of… Show more

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