Human papillomavirus genotype distribution and factors associated among female sex workers in West Africa

Tounkara, Fatoumata Korika; Teguété, Ibrahima; Goma-Matsétsé, Ella; Koné, A.; Béhanzin, Luc; Traoré, Sidy; Aza-Gnandji, Marlène; Keïta, Bintou Dembélé; Guénoun, Julie; Coutlée, François; Alary, Michel

doi:10.1371/journal.pone.0242711

Cited by 17 publications

(21 citation statements)

References 44 publications

(61 reference statements)

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“…The present study was combined with another one investigating cervical cancer and human papillomavirus (HPV) infection among FSWs [21]. Women were referred by peer educators to FSW-friendly clinics Dispensaire IST (DIST) in Cotonou, Benin, and Clinique des Halles run by ARCAD/SIDA, a national Non-Governmental Organisation (NGO), in Bamako, Mali for cervical cancer screening.…”

Section: Methodsmentioning

confidence: 99%

Reproductive History and Pregnancy Incidence of Malian and Beninese Sex Workers Before and Suring Sex Work Practice

Sullivan¹,

Tounkara²,

Béhanzin³

et al. 2021

Preprint

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BACKGROUND: To reduce maternal mortality, access to family planning and reproductive health care services is a key strategy. Access to and use by marginalized populations pose a substantial challenge. Sex workers in sub-Saharan Africa are a good example. The objective of this study was to describe the reproductive history of female sex workers (FSWs) before and during sex work.METHODS: FSWs aged ≥18 years were recruited in Cotonou (Benin), and Bamako (Mali), to answer a face-to-face questionnaire inquiring on reproductive history. Descriptive analyses were carried out and comparisons made between countries using Pearson chi-square and between the periods before (BSW) and during sex work (DSW) practice within women in each country using McNemar chi-square. In addition, multiple imputations were used to estimate and compare the incidence rate of pregnancy BSW and DSW.RESULTS: Mean age was 26 years in Mali (n=322) and 35 years in Benin (n=330). More women had at least one pregnancy BSW compared to DSW in both Mali (62.1% vs 33.5%) and Benin (91.2% vs 32.7%). The pregnancies occurring DSW had lower livebirth rates (57.9% vs 74.7% - Mali, 17.6% vs 60.6% - Benin) and ended more often with a therapeutic abortion, DSW compared to BSW, especially in Benin (65.2% vs 25.6%). The level of complications associated with therapeutic abortion was high, both DSW (23%) and BSW (20%). The incidence rate of pregnancy was about twice lower DSW compared to BSW [incidence rate ratio (IRR): 0.49; 95% confidence interval (95%CI): 0.37-0.66 in Mali and IRR: 0.45; 95% CI: 0.32-0.63 in Benin].CONCLUSION: In both Benin and Mali, FSWs had more pregnancies during the period preceding sex work practice, about twice more than during sex work when considering the differences in incidence rates. Single mothers need to be supported to avoid sex work as a financial solution. On the other hand, the reproductive needs of FSWs need to be acknowledged to reduce maternal mortality within this marginalized population. It is of paramount importance that interventions remain focused on reproductive health and prevent unwanted pregnancies, answer contraceptive needs and provide safe therapeutic abortions.

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Section: Methodsmentioning

confidence: 99%

Reproductive History and Pregnancy Incidence of Malian and Beninese Sex Workers Before and Suring Sex Work Practice

Sullivan¹,

Tounkara²,

Béhanzin³

et al. 2021

Preprint

Self Cite

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“…At each visit, a structured questionnaire was administered face-to-face by qualified interviewers. Data on sociodemographic, behavioral and sex work characteristics were collected, as well as obstetrical and reproductive history (see previous papers for more details (Tounkara et al 2020a, Tounkara et al 2020b. Each visit also included gynecological examination, vaginal and cervical swabs collection for curable STI testing.…”

Section: Data Collectionmentioning

confidence: 99%

“…All women were screened for abnormal cervical lesions using visual inspection with acetic acid and Lugol's iodine (VIA/VILI). A venous blood sample (3 ml) was collected for HIV testing (see previous papers for more details on storage process and banking of specimens (Tounkara et al 2020a, Tounkara et al 2020b.…”

Section: Data Collectionmentioning

confidence: 99%

“…In fact, our previous data showed an overall HPV prevalence of 95.5% in Benin and 81.4% in Mali, while HIV prevalence was 26.3% in Benin versus 20.4% in Mali. In addition, the prevalence of other STIs, such as Neisseria gonorrhoeae, Chlamydia trachomatis and Trichomonas vaginalis, was 13.8%, 7.4% and 1.6%, respectively, in Benin, and 24.2%, 14.0% and 3.7%, respectively, in Mali (Tounkara et al 2020a). The presence of STIs increase the probability of HPV acquisition and its persistence.…”

Section: Introductionmentioning

confidence: 99%

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Type-specific incidence, persistence and factors associated with human papillomavirus infection among female sex workers in Benin and Mali, West Africa

Tounkara

Teguété

Talbot

et al. 2021

International Journal of Infectious Diseases

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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“…Nearly 70% of cervical cancers worldwide are related to high oncogenic risk (HR)-HPV genotypes 16 and 18, but at least 11 other HR-HPV types are also known to be associated with cervical cancer [ 2 , 3 ]. The distribution of HR-HPV genotypes varies by geographic area, demographics, and sexual risk behaviors [ 4 , 5 , 6 ]. Most HPV infections are cleared spontaneously but may persist and induce the development of precancerous and cancerous lesions [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Cervical Human Papillomavirus Infection (HPV) and High Oncogenic Risk Genotypes among Women Living with HIV in Asia: A Meta-Analysis

Verrier

Cœur

Delory

2021

JCM

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Women living with HIV (WLHIV) are prone to harbor several high-risk human papillomavirus (HR-HPV) genotypes and to develop cervical cancerous lesions. Data on HPV prevalence in these women are needed to inform immunization programs, especially in Asia where few data are available. We conducted a systematic review and meta-analysis to estimate the prevalence of HPV and HR-HPV cervical infection in WLHIV in Asia and identify possible sources of heterogeneity for HR-HPV carriage. Pooled prevalence and its 95% confidence interval (95CI) were estimated using the inverse-variance weighting method. Linear regression weighted on study size was used to identify sources of heterogeneity. Among 7834 WLHIV (40 studies), the prevalence of HPV infection was 42.6% (95CI, 38.2% to 47.1%), and 34.6% (95CI, 30.3% to 39.1%) harbored HR-HPV genotypes, with significant heterogeneity across countries. In India, Thailand, and China, HPV-16 was the most frequent genotype (10.3%), followed by HPV-52 (5.4%), HPV-58 (5.0%), HPV-18 (4.1%), and HPV-33 (3.3%). In these women, most of whom were receiving antiretroviral therapy, we did not identify determinants of heterogeneity for HR-HPV infection. Our results underline the need for immunization programs based on nonavalent or new generation vaccines to prevent cervical cancer in WLHIV in Asia.

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Human papillomavirus genotype distribution and factors associated among female sex workers in West Africa

Cited by 17 publications

References 44 publications

Reproductive History and Pregnancy Incidence of Malian and Beninese Sex Workers Before and Suring Sex Work Practice

Reproductive History and Pregnancy Incidence of Malian and Beninese Sex Workers Before and Suring Sex Work Practice

Type-specific incidence, persistence and factors associated with human papillomavirus infection among female sex workers in Benin and Mali, West Africa

Cervical Human Papillomavirus Infection (HPV) and High Oncogenic Risk Genotypes among Women Living with HIV in Asia: A Meta-Analysis

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