Hybrid pregnant reference phantom series based on adult female ICRP reference phantom

Rafat-Motavalli, Laleh; Hakimabad, Seyyed Hashem Miri; Hoseinian-Azghadi, Elie

doi:10.1016/j.radphyschem.2017.10.001

Cited by 10 publications

(14 citation statements)

References 11 publications

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“…This study utilized a set of realistic computational phantoms of pregnant patients at the end of three gestational periods of 3, 6, and 9 months as illustrated in Fig. , which have been previously developed . The general anatomy of these phantoms is based on the adult female ICRP reference phantom, which was deformed in the abdominal‐pelvic region to represent pregnant models.…”

Section: Methodsmentioning

confidence: 99%

“…The models of the fetus and enlarged uterus were constructed with the help of MR images of pregnant subjects. Further information about phantoms’ construction can be found in our previous paper …”

Section: Methodsmentioning

confidence: 99%

“…1, which have been previously developed. 16,20 The general anatomy of these phantoms is based on the adult female ICRP reference phantom, which was deformed in the abdominal-pelvic region to represent pregnant models. These phantoms were carefully adjusted by modifying organ volumes and masses of pregnant phantoms to agree with reference values recommended in the ICRP Publication 89.…”

Section: A Pregnant Phantom Seriesmentioning

confidence: 99%

“…With this context in mind, the question arises as to whether V/Q SPECT always outweighs CTPA in terms of dose to fetal or radiosensitive maternal organs. So, there is a need to conduct further study on radiation doses involving detailed geometrical simulation of pregnant women and the fetus with the help of our recently developed phantoms . The aim of this study was therefore to quantify radiation dose using our recently developed pregnant reference phantoms and to compare these findings with the literature.…”

Section: Introductionmentioning

confidence: 99%

“…So, there is a need to conduct further study on radiation doses involving detailed geometrical simulation of pregnant women and the fetus with the help of our recently developed phantoms. 16,20 The aim of this study was therefore to quantify radiation dose using our recently developed pregnant reference phantoms and to compare these findings with the literature. As part of our contribution, we also provided a formalism to calculate dose after a specific CTPA or V/Q SPECT procedure prescribed for a pregnant patient and relate these findings to the advice given in the forthcoming recommendations for management of PE.…”

Section: Introductionmentioning

confidence: 99%

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Pulmonary embolism in pregnant patients: Assessing organ dose to pregnant phantom and its fetus during lung imaging

et al. 2017

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: A Pregnant Phantom Seriesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pulmonary embolism in pregnant patients: Assessing organ dose to pregnant phantom and its fetus during lung imaging

et al. 2017

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Construction of a digital fetus library for radiation dosimetry

Xie

Giger

et al. 2022

Medical Physics

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Accurate estimations of fetal absorbed dose and radiation risks are crucial for radiation protection and important for radiological imaging research owing to the high radiosensitivity of the fetus. Computational anthropomorphic models have been widely used in patient-specific radiation dosimetry calculations. In this work, we aim to build the first digital fetal library for more reliable and accurate radiation dosimetry studies. Acquisition and validation methods: Computed tomography (CT) images of abdominal and pelvic regions of 46 pregnant females were segmented by experienced medical physicists. The segmented tissues/organs include the body contour, skeleton, uterus, liver, kidney, intestine, stomach, lung, bladder, gall bladder, spleen, and pancreas for maternal body, and placenta, amniotic fluid, fetal body, fetal brain, and fetal skeleton. Nonuniform rational B-spline (NURBS) surfaces of each identified region was constructed manually using 3D modeling software. The Hounsfield unit values of each identified organs were gathered from CT images of pregnant patients and converted to tissue density. Organ volumes were further adjusted according to reference measurements for the developing fetus recommended by the World Health Organization (WHO) and International Commission on Radiological Protection. A series of anatomical parameters, including femur length, humerus length, biparietal diameter, abdominal circumference (FAC), and head circumference, were measured and compared with WHO recommendations. Data format and usage notes: The first fetal patient-specific model library was developed with the anatomical characteristics of each model derived from the corresponding patient whose gestational age varies between 8 and 35 weeks. Voxelized models are represented in the form of MCNP matrix input files representing the three-dimensional model of the fetus. The size distributions of each model are also provided in text files. All data are stored on Zenodo and are publicly accessible on the following link: https://zenodo.org/record/6471884. Potential applications: The constructed fetal models and maternal anatomical characteristics are consistent with the corresponding patients. The resulting computational fetus could be used in radiation dosimetry studies to improve the reliability of fetal dosimetry and radiation risks assessment. The advantages of NURBS surfaces in terms of adapting fetal postures and positions enable us to adequately assess their impact on radiation dosimetry calculations. K E Y W O R D S computational model, CT, fetus, pregnant patients, radiation dose Shuiyin Qu and Tianwu Xie contributed equally to the work.

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Patient‐specific fetal radiation dosimetry for pregnant patients undergoing abdominal and pelvic CT imaging

Liu

Xie

et al. 2023

Medical Physics

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Background: Accurate estimation of fetal radiation dose is crucial for riskbenefit analysis of radiological imaging, while the radiation dosimetry studies based on individual pregnant patient are highly desired. Purpose: To use Monte Carlo calculations for estimation of fetal radiation dose from abdominal and pelvic computed tomography (CT) examinations for a population of patients with a range of variations in patients' anatomy, abdominal circumference, gestational age (GA), fetal depth (FD), and fetal development. Methods: Forty-four patient-specific pregnant female models were constructed based on CT imaging data of pregnant patients, with gestational ages ranging from 8 to 35 weeks. The simulation of abdominal and pelvic helical CT examinations was performed on three validated commercial scanner systems to calculate organ-level fetal radiation dose. Results:The absorbed radiation dose to the fetus ranged between 0.97 and 2.24 mGy, with an average of 1.63 ± 0.33 mGy. The CTDI vol -normalized fetal dose ranged between 0.56 and 1.30, with an average of 0.94 ± 0.25. The normalized fetal organ dose showed significant correlations with gestational age, maternal abdominal circumference (MAC), and fetal depth. The use of ATCM technique increased the fetal radiation dose in some patients. Conclusion:A technique enabling the calculation of organ-level radiation dose to the fetus was developed from models of actual anatomy representing a range of gestational age,maternal size,and fetal position.The developed maternal and fetal models provide a basis for reliable and accurate radiation dose estimation to fetal organs.

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Hybrid pregnant reference phantom series based on adult female ICRP reference phantom

Cited by 10 publications

References 11 publications

Pulmonary embolism in pregnant patients: Assessing organ dose to pregnant phantom and its fetus during lung imaging

Pulmonary embolism in pregnant patients: Assessing organ dose to pregnant phantom and its fetus during lung imaging

Construction of a digital fetus library for radiation dosimetry

Patient‐specific fetal radiation dosimetry for pregnant patients undergoing abdominal and pelvic CT imaging

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