Hydatid cyst in children: A 10-year experience from Iran

Aslanabadi, Saeid; Zarrintan, Sina; Abdoli-Oskouei, Shahram; Salehpour, Firooz; Zarrintan, Armin; Beheshtirouy, Samad; Abdollahi, Habib; Badebarin, Davoud

doi:10.4103/0189-6725.115040

Cited by 24 publications

(14 citation statements)

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“…Most studies (15 articles) were from Tehran ( n = 79867) [71–85], seven were from Khorasan Razavi ( n =3328) [47–52, 90], six were from East Azerbaijan ( n = 2565) [26–30], four each were from Isfahan ( n =1581) [40, 91, 92] and Lorestan (65322) [59–61], three each were from Mazandaran ( n =773) [63–65], Kerman ( n =1573) [42–44], Ardabil ( n =3671) [21–23], and Hamedan ( n =1733) [37, 38, 93], two each were from Chaharmahal and Bakhtiari ( n =2668) [24, 25], Fars ( n =4391) [31–34], Guilan (214) [3, 35], Kermanshah ( n =698) [45, 46], Khuzestan ( n =3486) [53, 54], Kohkiluyeh and Buyer Ahmad ( n = 605) [55, 56], Kurdistan ( n =3093) [57, 58], Qom ( n =1646) [67, 68], Sistan and Baluchestan ( n =585) [69, 70], one each were from Golestan ( n =1024) [36], Ilam ( n =3000) [39], Markazi ( n =578) [62], North Khorasan ( n =24) [66], West Azerbaijan ( n =294) [87], Yazd ( n =26911) [88], and Zanjan ( n =136) [89]. One study was performed in both Ardabil and East Azerbaijan ( n =59) [20], one study reported the number of hydatidosis infected patients admitted to eight major referral hospitals in Isfahan, Tehran, Sistan and Baluchestan, Kurdistan, Kermanshah, Hamedan, and Markazi ( n =161) [41], and finally, one study examined the serum samples of healthy volunteers from 8 different western provinces of Iran including Ardabil, East Azerbaijan, West Azerbaijan, Ilam, Kurdistan, Hamedan, and Lorestan ( n =4138) [86](Tables 1 and 2).…”

Section: Resultsmentioning

confidence: 99%

Epidemiology of echinococcosis in Iran: a systematic review and meta-analysis

et al. 2019

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BackgroundEchinococcosis is a zoonotic disease caused by the larval stages of taeniid cestodes of the genus Echinococcus. The two major types of infection in humans are cystic echinococcosis (CE) or hydatidosis and alveolar echinococcosis (AE). It is endemic in some parts of the world, such as the Middle East, with Iran being a part of it. This systematic review and meta-analysis were conducted to determine the prevalence of CE and AE echinococcosis and their epidemiological and clinical aspects in Iran.MethodsElectronic databases, including MEDLINE (via PubMed), SCOPUS, Web of Science, SID and Mag Iran (two Persian scientific search engines) were searched from 1 January 1990 to 8 August 2017. The prevalence of CE and AE echinococcosis was estimated using the random effects meta-analysis. Heterogeneity was evaluated by subgroup analysis. Data were analyzed by STATA version 12.ResultsOf the 2051 records identified in the mentioned electronic databases, Seventy-eight articles met our eligibility criteria, with a total of 214124individuals. The meta-analysis was performed on only 37 out of 78 included studies. The pooled prevalence of CE and AE in Iran was 5% [95% confidence interval )CI(: 3-6%] and 2% [95% CI: 0-5%], respectively. Subgroup meta-analysis revealed that the prevalence of CE was significantly higher in North [9%, 95% CI: 4-18%] and West of Iran [6%, 95% CI: 3-11%], patients younger than 40 years of age [7%, 95% CI: 4-12%], villagers and nomads [6%, 95% CI: 2-12%], and studies that used the combination of serological, clinical, and imaging diagnostic methods [7%, 95% CI: 5-9%]. There were no significant differences between the prevalence of CE among low and high-quality studies. Housewives were the most affected group by hydatidosis (n=24/77, 31%), followed by illiterate people (n=11/77, 14%) and farmers (n= 9/77, 12%). Liver [55%, 95% CI: 46-65%] and lung [28%, 95% CI, 22-35%] were the most common sites of cyst formation.ConclusionsGiven to the importance of echinococcosis on human health and domestic animals industry, it is necessary to implement monitoring and control measures in this regard.

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Section: Resultsmentioning

confidence: 99%

Epidemiology of echinococcosis in Iran: a systematic review and meta-analysis

et al. 2019

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“…Human hydatid disease, or cystic echinococcosis (CE), is a worldwide health problem, especially in regions where dogs, sheep and cattle are common livestock, such as South America, Australia, India, the Middle East, sub-Saharan Africa and the Mediterranean countries, including Turkey. [1][2][3][4] The World Health Organization states that over 1 million individuals are infected with Echinococcus worldwide annually. [5] The epidemiology of CE is poorly understood in South Africa (SA).…”

Section: Articlementioning

confidence: 99%

“…[3,9] Several studies have indicated that major symptoms of pulmonary hydatidosis are related to the mass effect from the cyst volume, and they include cough, fever, chest pain, dyspnoea, mucopurulent sputum and haemoptysis. [1,3] The principal complication is cyst rupture and resultant spillage of protoscolices into the bronchial tree, producing cough and haemoptysis. Rupture into pleural space produces pleural effusion and empyema.…”

Section: Articlementioning

confidence: 99%

Pulmonary Hydatidosis- Still Unrecognized in Endemic Regions: A 10 Year Review.

et al. 2018

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Background. Echinococcus disease in still endemic in many low-middle-income countries, with 1 million people infected at any one time. Surgery, the mainstay of its treatment, is costly. Objectives. To describe the presentation, clinical features and outcomes of children referred with pulmonary hydatid disease at Inkosi Albert Luthuli Central Hospital in Durban, South Africa. Methods. A 10-year review of children with pulmonary hydatid disease at Inkosi Albert Luthuli Hospital was carried out. The data collected were demographic, clinical, laboratory and radiological. Cases were mapped geographically to analyse for clustering of cases. Spearman's correlation was used to assess for correlations between laboratory markers. Results. A total of 24 subjects, 75% of whom were male, were included. The mean (standard deviation) age at diagnosis was 8.9 (3.4) years. The mean delay in diagnosis was 5.8 (5.7) months. Of the subjects, 15 (71.4%) were from the Eastern Cape and 9 from KwaZulu-Natal provinces. Seventy-nine percent of the patients had been exposed to dogs, while 8% reported exposure to either sheep or cattle. There was right-sided preponderance, with 11 right-and 7 left-sided cysts; 6 patients had bilateral cysts, and 4 associated extrapulmonary cysts. Indirect haemagglutination assay was positive in 70%, and blood eosinophilia was present in 45% of the subjects, with no correlation between the two markers (p=0.22). Surgery was the only modality of treatment in 18 (75%) subjects, while 5 had had prior medical therapy for disseminated disease. The mean intensive care stay postoperatively was 2 (2) days with no mortality. Conclusion. Despite exposure to known risk factors and living in endemic regions, there is often a significant delay in diagnosis of pulmonary hydatid disease at Inkosi Albert Luthuli Hospital.

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“…However, the incidence of the disease has increased over the past decades because of massive migration and high tourist traffic, especially in Europe and North America. 5,17…”

Section: Introductionmentioning

confidence: 99%

Echinococcus Granulosus in Childhood: A Retrospective Study of 187 Cases and Newer Data

Πετρόπουλος

Chatzoulis

2019

Clin Pediatr (Phila)

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Echinococcus granulosus, first reported by Goeze in 1782, is the causative parasite of cystic echinococcosis (hydatidosis) especially for countries that are endemic areas. Since the 1970s, the incidence of echinococcosis in Greece has been very high. Nevertheless, with the implementation of special prevention measures in the 1980s, a large reduction in the incidence of hydatidosis meant that it reached European levels. Therefore, we analyzed the demographics, multiple organ localizations of the parasite, diagnosis, and conservative and optimal surgical treatment over a total period of 39 years, especially for pulmonary and hepatic echinococcosis in children. The higher incidence of pulmonary echinococcosis compared with other localizations, male predominance, wide range of age, and various cystic sizes were some of the main demographics. Because cystic echinococcosis remains a main public health problem, we advocate a meticulous clinical investigation and treatment methodology to bridge the gap between knowledge and awareness of this important disease.

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Hydatid cyst in children: A 10-year experience from Iran

Abstract: Lung hydatidosis is more common than hepatic hydatidosis in children than adults and it is more frequent in males. Hydatid disease should be considered in differential diagnoses of liver and lung cystic lesions in children.

Cited by 24 publications

References 9 publications

Epidemiology of echinococcosis in Iran: a systematic review and meta-analysis

Epidemiology of echinococcosis in Iran: a systematic review and meta-analysis

Pulmonary Hydatidosis- Still Unrecognized in Endemic Regions: A 10 Year Review.

Echinococcus Granulosus in Childhood: A Retrospective Study of 187 Cases and Newer Data

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