Hydrocarbon polymer analysis by external MALDI fourier transform and reflectron time of flight mass spectrometry

Jaber, Arwah J.; Wilkins, Charles L.

doi:10.1016/j.jasms.2005.08.006

Cited by 18 publications

(14 citation statements)

References 29 publications

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“…The continual refinement and upgrading of mass spectrometry (MS) techniques has provided considerable impetus in determining the composition, molecular weight distribution (MWD) and structure of carbonaceous species. As a powerful new method for analyzing high molecular weight materials, matrix-assisted laser desorption ionization (MALDI) is pertinent to the characterization of polymers (Belu et al, 1996;Tanaka et al, 1988;Jaber and Wilkins, 2005;Trimpin et al, 2006;Klein et al, 2006). In general, MALDI-MS has been successful in analyzing polar synthetic polymers since they have a high chemical resemblance to biopolymers, for which the MALDI technique was originally developed, and they contain heteroatoms such as N or O which provide sites for proton or metal cation attachment (Belu et al, 1996;Yalcin and Dai, 1998).…”

Section: Introductionmentioning

confidence: 99%

Contribution of mass spectrometry in assessing quality of petroleum fractions

Pantoja

Mendes

Nascimento

2013

Journal of Petroleum Science and Engineering

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Section: Introductionmentioning

confidence: 99%

Contribution of mass spectrometry in assessing quality of petroleum fractions

Pantoja

Mendes

Nascimento

2013

Journal of Petroleum Science and Engineering

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“…Although the superb resolving power and mass accuracy of FTICR-MS make it an eminently useful technique, MALDI-FTICR-MS is not ideal for polymer analysis at this stage. In fact, only a few polymer characterizations by MALDI-FTICR-MS have been described [20–23], and, to our knowledge, no use of KMD analysis for polymer characterization has yet been reported.…”

Section: Introductionmentioning

confidence: 99%

Structural Characterization of Polymers by MALDI Spiral-TOF Mass Spectrometry Combined with Kendrick Mass Defect Analysis

Sato

Nakamura

Teramoto

et al. 2014

J. Am. Soc. Mass Spectrom.

127

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High-resolution mass spectrometry (HRMS) continues to play an important role in the compositional characterization of larger organic molecules. In the field of polymer characterization, however, the application of HRMS has made only slow progress because of lower compatibility between matrix-assisted laser desorption/ionization (MALDI) and ultrahigh-resolution Fourier transform ion cyclotron resonance mass spectrometry (FT-ICRMS). In this study, a newly developed type of MALDI high-resolution time-of-flight mass spectrometry (TOFMS) with a spiral ion trajectory (MALDI spiral-TOFMS) was applied to the structural and compositional characterization of polymers. To create a graphical distribution of polymer components on a two-dimensional plot converted from complex mass spectra, we adopted a slightly modified Kendrick mass defect (KMD) analysis based on accurate masses determined using spiral-TOFMS. By setting the Kendrick mass scale based on the mass of the repeating units of a given polymer, components with common repeat units lined up in the horizontal direction on the KMD plot, whereas those components with different structures were shifted vertically. This combination of MALDI spiral-TOFMS measurement and KMD analysis enabled the successful discrimination of the polymer components in a blend of poly(alkylene oxide)s, the compositional analysis of poly(ethylene oxide)/poly(propylene oxide) block copolymers, and profiling of the end-group distribution of poly(ε-caprolactone)s synthesized under different conditions.ᅟ

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“…However, direct MS is a powerful alternative for samples of low complexity or for high‐throughput screening approaches. Desorption/ionization MS techniques are very useful in this respect, including nowadays seldom used field desorption, desorption electrospray, desorption atmospheric pressure photoionization, laser desorption/ionization and matrix‐assisted laser desorption/ionization (MALDI) . Desorption/ionization MS techniques are also indispensable for MS imaging (MSI) .…”

Section: Introductionmentioning

confidence: 99%

“…Desorption/ionization MS techniques are very useful in this respect, including nowadays seldom used field desorption, [24,25] desorption electrospray, [26,27] desorption atmospheric pressure photoionization, [28] laser desorption/ionization [29][30][31][32] and matrixassisted laser desorption/ionization (MALDI). [33][34][35][36][37][38] Desorption/ ionization MS techniques are also indispensable for MS imaging (MSI). [39][40][41][42] As regards MALDI and long-chain neutral lipids, addition of silver salts to the sample yields [M + Ag] + ions.…”

Section: Introductionmentioning

confidence: 99%

New MALDI matrices based on lithium salts for the analysis of hydrocarbons and wax esters

et al. 2014

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Lithium salts of organic aromatic acids (lithium benzoate, lithium salicylate, lithium vanillate, lithium 2,5-dimethoxybenzoate, lithium 2,5-dihydroxyterephthalate, lithium α-cyano-4-hydroxycinnamate and lithium sinapate) were synthesized and tested as potential matrices for the matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry analysis of hydrocarbons and wax esters. The analytes were desorbed using nitrogen laser (337.1 nm) and ionized via the attachment of a lithium cation, yielding [M + Li](+) adducts. The sample preparation and the experimental conditions were optimized for each matrix using stearyl behenate and n-triacontane standards. The performance of the new matrices in terms of signal intensity and reproducibility, the mass range occupied by matrix ions and the laser power threshold were studied and compared with a previously recommended lithium 2,5-dihydroxybenzoate matrix (LiDHB) (Cvačka and Svatoš, Rapid Commun. Mass Spectrom. 2003, 17, 2203). Several of the new matrices performed better than LiDHB. Lithium vanillate offered a 2-3 times and 7-9 times higher signal for wax esters and hydrocarbons, respectively. Also, the signal reproducibility improved substantially, making this matrix a suitable candidate for imaging applications. In addition, the diffuse reflectance spectra and solubility of the synthesized compounds were investigated and discussed with respect to the compound's ability to serve as MALDI matrices. The applicability of selected matrices was tested on natural samples of wax esters and hydrocarbons.

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Hydrocarbon polymer analysis by external MALDI fourier transform and reflectron time of flight mass spectrometry

Cited by 18 publications

References 29 publications

Contribution of mass spectrometry in assessing quality of petroleum fractions

Contribution of mass spectrometry in assessing quality of petroleum fractions

Structural Characterization of Polymers by MALDI Spiral-TOF Mass Spectrometry Combined with Kendrick Mass Defect Analysis

New MALDI matrices based on lithium salts for the analysis of hydrocarbons and wax esters

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