Hydrodynamics, heat and mass transfer during coating of tablets in a spouted bed

Kucharski, J.; Kmieć, Andrzej

doi:10.1002/cjce.5450610326

Cited by 47 publications

(19 citation statements)

References 4 publications

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“…Nowadays they are used for drying grain agricultural products (Devahastin et al 1998;Kudra et al 2001), dispersed materials (Kmiec and Szafran 2000), paste-like materials on inert bodies (Kudra et al 1989;Arsenijevic et al 2004), slurries and solutions (Tia et al 1995). The SB dryers have also been used for coating particles to obtain products with special properties, such as tablets (Kucharski and Kmiec 1983;Publio and Oliveira 2004). A special area of application of this type of equipment in the pharmaceutical industry is the coating operation for producing functional particles of around 30 µm, which can be used, for example, as injectable suspensions for cancer therapy (Arimoto et al 2004).…”

mentioning

confidence: 98%

Periodic Fluctuations of Flow and Porosity in Spouted Beds

Szafran

Kmieć

2006

Transp Porous Med

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The results of experimental investigations of bed flow hydrodynamics in spouted beds are compared with CFD simulations (Eulerian-Eulerian approach) for two different column geometries. The experimental results of bed porosity and fluctuation frequency of mass flow rate of grain in the fountain region are compared with the corresponding results of simulations. The simulation results confirmed the observations of Muir et al. (1990, Chem. Eng. Comm. 88: 153-171) and Yang and Keairns (1978, AlchE Symp. Ser. No. 176 74: 218) that fluctuations of bed flow in DTSB are caused by particle cluster formation in the loading region at the bottom of column.The solids cross into the jet and cover the column inlet and are carried upward periodically through a draft tube. Subsequent figures obtained from simulations, which show stages of particle cluster formation at the entrance of column, exactly match visual observations. The frequency of fluctuations of grain mass flow rate predicted in simulations (∼5-6 Hz) is in the range of that experimentally determined. The fluctuating inflow of solids results in slug formation and explains the vertical variations of height and porosity of the fountain. NotationGravity acceleration (m/s 2 ) h bed Initial height of bed (m) = I Identity tensor

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confidence: 98%

Periodic Fluctuations of Flow and Porosity in Spouted Beds

Szafran

Kmieć

2006

Transp Porous Med

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“…(8) with the experimental data indicates the Reynolds number exponent found to be 0.779 whilst the Reynolds number exponents in conventional spouted beds reported in literature are given in the typical range of 0.47-0.64 (Kmiec, 1975;Kucharski & Kmiec, 1983). This implies the transfer of heat in the spout region for the two-dimensional spouted bed to be governed by the relative combined effects of lamina and turbulent boundary layers.…”

Section: Heat Transfer In Spout Regionmentioning

confidence: 88%

Characteristics of heat transfer in two-dimensional spouted bed

Prachayawarakorn

Ruengnarong

Soponronnarit

2006

Journal of Food Engineering

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“…The technology today has been successfully applied to the drying of paste, granulation, tablet coating, combustion and gasification of coal and other chemical processes [1][2][3][4]. One of its advantages is that it can guarantee good contacts between gas and solid particles.…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of two-dimensional spouted bed with draft plates by discrete element method

Zhao

Cheng

Jiang

et al. 2008

Front. Chem. Eng. China

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A discrete element method (DEM)-computational fluid dynamics (CFD) two-way coupling method was employed to simulate the hydrodynamics in a twodimensional spouted bed with draft plates. The motion of particles was modeled by the DEM and the gas flow was modeled by the Navier-Stokes equation. The interactions between gas and particles were considered using a twoway coupling method. The motion of particles in the spouted bed with complex geometry was solved by combining DEM and boundary element method (BEM). The minimal spouted velocity was obtained by the BEM-DEM-CFD simulation and the variation of the flow pattern in the bed with different superficial gas velocity was studied. The relationship between the pressure drop of the spouted bed and the superficial gas velocity was achieved from the simulations. The radial profile of the averaged vertical velocities of particles and the profile of the averaged void fraction in the spout and the annulus were statistically analyzed. The flow characteristics of the gas-solid system in the two-dimensional spouted bed were clearly described by the simulation results.

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Hydrodynamics, heat and mass transfer during coating of tablets in a spouted bed

Cited by 47 publications

References 4 publications

Periodic Fluctuations of Flow and Porosity in Spouted Beds

Periodic Fluctuations of Flow and Porosity in Spouted Beds

Characteristics of heat transfer in two-dimensional spouted bed

Numerical simulation of two-dimensional spouted bed with draft plates by discrete element method

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