Hydrogen Peroxide Stability in Silica Hydrogels

Abstract

Hydrogen peroxide (H 2 O 2 ) entrapment in silica hydrogels has potential to be used in various industrially important applications to increase H 2 O 2 stability. In this study, optimum conditions for hydrogel formation and H 2 O 2 stability were determined by varying the sodium content and initial H 2 O 2 concentration. Higher retention and better stability of H 2 O 2 were achieved with hydrogels at room temperature at low sodium concentration. Retention values of 89% were obtained with initial H 2 O 2 concentrations up to 10 wt %. H 2 O 2 decomposition in hydrogels followed a first-order reaction. Hydrogels were characterized by measuring their surface area, pore size, and pore size distribution by Brunauer−Emmett−Teller analysis and scanning electron microscopy. Mesoporous (3−24 nm) hydrogels with high surface area (1000−1400 m 2 /g) were obtained. In addition, the melting point of the entrapped H 2 O 2 -water mixture in the hydrogels was studied by low temperature differential scanning calorimetry.

Hydrogen Peroxide: A Key Chemical for Today's Sustainable Development

“…One promising approach was introduced by Ż egliń ski and co-workersi n2 007, who described the prolonged antibacterial activity of silica xerogels entrapping 3.8 %H 2 O 2 ,w hich, stored at room temperature, retained 71 %o ft he entrapped peroxide after 63 days; [54] the same composite could be successfully used in place of 30 %H 2 O 2 in selective oxidation reactions. [57] More than 70 %o fH 2 O 2 was retained after 40 days of storage at room temperature ( Figure 9);t his shows that sol-gele ncapsulation in silica gels can be used to store high concentrations of H 2 O 2 in as table solid form. [57] More than 70 %o fH 2 O 2 was retained after 40 days of storage at room temperature ( Figure 9);t his shows that sol-gele ncapsulation in silica gels can be used to store high concentrations of H 2 O 2 in as table solid form.…”

Stabilization and Controlled Release of Microencasulated Hydrogen Peroxide for Wound Treatment Applications

“…Sudur et al . (), Sudur and Orbey () and Dogan et al . () observed that the amount and type of ions in the precursor during micro‐encapsulation has a major effect on the release rate from silica hydrogels.…”

“…Sudur et al . () evaluated the antimicrobial activity of H 2 O 2 ‐encapsulated hydrogels against Escherichia coli using the agar well diffusion method. Early experiments showed significant antimicrobial activity after 4 months of storage in a closed container at room temperature.…”

“…The controlled release of H 2 O 2 from hydrogels over extended periods of time may result in less frequent wound dressing changes, decreasing the risk of disrupting the delicate healing process. Sudur et al (2015a) evaluated the antimicrobial activity of H 2 O 2 -encapsulated hydrogels against Escherichia coli using the agar well diffusion method. Early experiments showed significant antimicrobial activity after 4 months of storage in a closed container at room temperature.…”

“…To more closely simulate bandaged wound conditions, the release of the H 2 O 2 into air at body temperature (37°C) and 35% initial relative humidity (RH) was studied. Sudur et al (2015b), Sudur and Orbey (2015c) and Dogan et al (2017) observed that the amount and type of ions in the precursor during micro-encapsulation has a major effect on the release rate from silica hydrogels. They concluded that the pore structure of the hydrogel and the release rate are closely related.…”