Hydropic Degenerating Leiomyoma Presenting as Pseudo-Meigs Syndrome With Elevated Ca 125

Abstract

Background: Leiomyomas rarely cause pseudo-Meigs syndrome. Increased levels of CA 125 often are associated with some types of malignancy. No reported case of pseudoMeigs syndrome presenting with hydropic degeneration of uterine leiomyoma and an elevated CA 125 level could be found on a MEDLINE search. Case: A 46-year-old woman presented with a pleural effusion and a pelvic mass measuring 30 ؋ ؋ ؋ 18 cm. Preoperative evaluation was remarkable for a CA 125 level of 254 U/mL. At laparotomy, the diagnosis was a benign leiomyoma with focal hyaline and extensive hydropic degeneration. Her pleural effusion resolved completely by 4 months postoperatively. Conclusion: Pseudo-Meigs syndrome can present with an elevated CA 125 level. (Obstet Gynecol 1998;92:648 -9.)

A rare case of Meigs syndrome in pregnancy with bilateral ovarian masses

“…These benign tumours include those of the fallopian tube or uterus or mature teratomas,struma ovarii or ovarian leiomyomas. 4 Surgical treatment includes unilateral salpingooophorectomy to total hysterectomy with b/l salpingooophorectomy depending upon age and parity of the patient and whether the tumour is u/l or b/l.…”

Concentrated ascites re‐infusion therapy for pseudo‐Meigs' syndrome complicated by massive ascites in large pedunculated uterine leiomyoma

“…This syndrome is an important consideration in the differential diagnosis of ovarian cancer, and rarely causes fatal manifestations . Only 32 studies on pseudo‐Meigs' syndrome complicated with uterine leiomyoma have been reported using a medline search (search terms: pseudo‐Meigs' and leiomyoma, leiomyoma and ascites) since 1900 (Table ) . The association of uterine leiomyoma with ascites and/or PE was first reviewed by Kelly and Cullen in 1909 .…”

Juvenile Granulosa Cell Tumor and High Blood Ca-125 Levels in Children with Pseudo-Meigs Syndrome

“…Meigs syndrome was first defined by J. V. Meigs (4,5). Pseudo-Meigs syndrome consists of pleural effusion, ascites, and a benign tumor of the ovary other than fibromas (6). Ascites and hydrothorax should be a collection of malignant fluid.…”