2011
DOI: 10.4028/www.scientific.net/kem.493-494.826
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Hydroxyapatite/Biopolymers Composite Scaffolds for Bone Tissue Engineering

Abstract: The application of a hybrid composite consisting of biopolymer and calcium phosphate, similar morphology and properties of natural bone, may be a way to solve the problem of the fragility of ceramics without reducing its mechanical properties, retaining the properties of biocompatibility and high bioactivity. This work aims at the preparation and characterization of three-dimensional scaffolds composite HA / biopolymers (chitosan and gelatin). The freeze-drying technique was employed in this study to obtain th… Show more

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“…The size of the cHAp clusters varies over a wide range (1-15 µm). There are many attempts to prepare hydroxyapatite-biopolymer composites with appropriate bioactive properties for biomedical use or for bone tissue engineering; however, the majority of them use poly(l-lactic acid) (PLLA), poly(e-caprolactone), chitosan, and gelatines matrices [60][61][62][63][64][65][66][67], and only a few of them apply PVP or CA [68][69][70]. There are many attempts to prepare hydroxyapatite-biopolymer composites with appropriate bioactive properties for biomedical use or for bone tissue engineering; however, the majority of them use poly(l-lactic acid) (PLLA), poly(e-caprolactone), chitosan, and gelatines matrices [60][61][62][63][64][65][66][67], and only a few of them apply PVP or CA [68][69][70].…”
Section: Morphological Characterisation Of Pure and Chap-loaded Pvp And Camentioning
confidence: 99%
“…The size of the cHAp clusters varies over a wide range (1-15 µm). There are many attempts to prepare hydroxyapatite-biopolymer composites with appropriate bioactive properties for biomedical use or for bone tissue engineering; however, the majority of them use poly(l-lactic acid) (PLLA), poly(e-caprolactone), chitosan, and gelatines matrices [60][61][62][63][64][65][66][67], and only a few of them apply PVP or CA [68][69][70]. There are many attempts to prepare hydroxyapatite-biopolymer composites with appropriate bioactive properties for biomedical use or for bone tissue engineering; however, the majority of them use poly(l-lactic acid) (PLLA), poly(e-caprolactone), chitosan, and gelatines matrices [60][61][62][63][64][65][66][67], and only a few of them apply PVP or CA [68][69][70].…”
Section: Morphological Characterisation Of Pure and Chap-loaded Pvp And Camentioning
confidence: 99%