2016
DOI: 10.1007/s10815-016-0841-y
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Hydroxypropyl cellulose supplementation in vitrification solutions: a prospective study with donor oocytes

Abstract: 70/73 (95.9%) vitrified MII oocytes exhibited morphologic survival 2 h post-warming, with 49 (70.0%) presented normal fertilization, compared to 105 of 146 (71.9%) MII fresh oocytes. Similar embryo quality was observed in both groups. A total of 18 embryos implanted, out of 38 embryos transferred (47.3%), resulting in 13 newborns.

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Cited by 6 publications
(2 citation statements)
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“…HPC is a polysaccharide with a variable length that can form a viscous gel at low temperatures because it has very similar physical properties as albumin-based formulations with certain molecular weight [ 9 ]. It is listed in a pharmacopeia and can be safely used because it is a general food additive and drug excipient [ 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…HPC is a polysaccharide with a variable length that can form a viscous gel at low temperatures because it has very similar physical properties as albumin-based formulations with certain molecular weight [ 9 ]. It is listed in a pharmacopeia and can be safely used because it is a general food additive and drug excipient [ 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…Since its introduction to the market in the late 1960s, HPC has become an established feedstock in the food , and pharmaceutical industries. Recent works reported applications to microfluidics, oocyte vitrification, , and the design of functional nanomaterials. …”
Section: Introductionmentioning
confidence: 99%