Hyperbaric Oxygen Therapy: An Effective Auxiliary Treatment Method for Large Jaw Cysts

Abstract

Background: To evaluate hyperbaric oxygen therapy (HBOT) on infection rates and repair rates during the treatment of large jaw cysts. Methods: A prospective randomized, non-blinded, controlled clinical trial included 90 patients with jaw cysts, randomly divided into three groups. Patients were treated with enucleations and bone substitute was used in the experimental and control groups. The experimental group received HBOT. The primary predictor variable was HBOT. The infection rate, repair rate, preoperative volume of the jaw cysts, age, and sex were statistically analyzed. The Fisher exact test was used to compare the infection rate and postoperative complications. The repair rate of the bone defects was analyzed using the repeatedmeasures analysis of variance and the least significant difference tests. The Kendall's coefficient of concordance and Kappa statistics were calculated to evaluate the consistency between the two investigators. Results: The infection rate was 3.4% in the experimental group, 14.3% in the blank group, and 32.1% in the control group (P<0.05). The repair rate in the experimental group was significantly higher than in the control and blank groups at 1, 3 and 6 months after surgery (P<0.05). Conclusion:The results showed that HBOT reduced the postoperative infection rate following the enucleation of large jaw cysts with bone substitute filling, and it also improved the bone repair rate.

Efficacy of Fenestration Decompression for the Treatment of Oral and Maxillofacial Cysts

“…Patients generally have nonspecific symptoms in the initial stage, while in the middle and late stages, cysts may expand and cause severe damage to the jaw tissue if left untreated. Moreover, teeth in the affected area may become loose and fall off, directly affecting the patient's facial appearance, oral health, and normal chewing function and even causing facial deformities and cancer that affect patient's quality of life to a great extent [ 15 ]. Therefore, early detection, diagnosis, and treatment are necessary to effectively improve the prognosis of patients.…”