Hyperbaric oxygen therapy for chronic wounds

Kranke, Peter; Bennett, Michael H; James, Marrissa Martyn-St; Schnabel, Alexander; Debus, Sebastian

doi:10.1002/14651858.cd004123.pub3

Cited by 112 publications

(78 citation statements)

References 55 publications

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“…HBO, DAİ'lerde iyileşme oranlarını artırmakta (125)(126)(127)(128), iyileşme süresini kısaltmakta (126), ampütasyon oranlarını düşürmektedir (129,130). Bu yönde yapılan sistematik analizlerde HBO'nun DA yarasının iyileşmesini artırdığı ortaya konulmakla birlikte çalışmaların sayıca yetersizliğine, çalışma tasarımlarındaki sorunlara, HBO tedavisi olanakları-nın kısıtlılığına ve maliyetinin yüksek olduğuna değinilmek-tedir (131)(132)(133)(134)(135)(136). Bununla birlikte ülkemizde HBO olanakları, başka ülkelerdekilerle karşılaştırılamayacak kadar çok sayıda ve yaygın durumdadır (137).…”

Section: Diğer Tedavilerunclassified

Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report

Saltoğlu¹,

Kılıçoğlu²,

Baktiroğlu³

et al. 2016

Klimik Dergisi

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Study Group for Diabetic Foot Infections of the Turkish Society of Clinical Microbiology and Infectious Diseases has called for collaboration of the relevant specialist societies and the Ministry of Health to issue a national consensus report on the diagnosis, treatment and prevention of diabetic foot (DF) wounds and diabetic foot infections (DFIs) in Turkey. In the periodical meetings of the assigned representatives from all the parties, various questions as to pathogenesis, microbiology, assessment and grading, treatment, prevention and control of diabetic foot were identified. Upon reviewing related literature and international guidelines, these questions were provided

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Section: Diğer Tedavilerunclassified

Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report

Saltoğlu¹,

Kılıçoğlu²,

Baktiroğlu³

et al. 2016

Klimik Dergisi

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“…Fifteen systematic reviews including 18 meta-analyses [17-20,22,24,27,28,35,38,46,47,57-59] (Table 4; Additional file 4) examined the proportion of patients with healed diabetic foot and leg ulcers. Eight of these had an AMSTAR score ≥8 [17,18,20,22,24,27,28,59].…”

Section: Resultsmentioning

confidence: 99%

Seeking effective interventions to treat complex wounds: an overview of systematic reviews

Tricco

Antony

Vafaei

et al. 2015

BMC Med

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BackgroundNumerous, often multi-faceted regimens are available for treating complex wounds, yet the evidence of these interventions is recondite across the literature. We aimed to identify effective interventions to treat complex wounds through an overview of systematic reviews.MethodsMEDLINE (OVID interface, 1946 until October 26, 2012), EMBASE (OVID interface, 1947 until October 26, 2012), and the Cochrane Database of Systematic Reviews (Issue 10 of 12, 2012) were searched on October 26, 2012. Systematic reviews that examined adults receiving care for their complex wounds were included. Two reviewers independently screened the literature, abstracted data, and assessed study quality using the Assessment of Multiple Systematic Reviews (AMSTAR) tool.ResultsOverall, 99 systematic reviews were included after screening 6,200 titles and abstracts and 422 full-texts; 54 were systematic reviews with a meta-analysis (including data on over 54,000 patients) and 45 were systematic reviews without a meta-analysis. Overall, 44% of included reviews were rated as being of high quality (AMSTAR score ≥8). Based on data from systematic reviews including a meta-analysis with an AMSTAR score ≥8, promising interventions for complex wounds were identified. These included bandages or stockings (multi-layer, high compression) and wound cleansing for venous leg ulcers; four-layer bandages for mixed arterial/venous leg ulcers; biologics, ultrasound, and hydrogel dressings for diabetic leg/foot ulcers; hydrocolloid dressings, electrotherapy, air-fluidized beds, and alternate foam mattresses for pressure ulcers; and silver dressings and ultrasound for unspecified mixed complex wounds. For surgical wound infections, topical negative pressure and vacuum-assisted closure were promising interventions, but this was based on evidence from moderate to low quality systematic reviews.ConclusionsNumerous interventions can be utilized for patients with varying types of complex wounds, yet few treatments were consistently effective across all outcomes throughout the literature. Clinicians and patients can use our results to tailor effective treatment according to type of complex wound. Network meta-analysis will be of benefit to decision-makers, as it will permit multiple treatment comparisons and ranking of the effectiveness of all interventions.Please see related article: http://dx.doi.org/10.1186/s12916-015-0326-3Electronic supplementary materialThe online version of this article (doi:10.1186/s12916-015-0288-5) contains supplementary material, which is available to authorized users.

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“…& Hyperbaric oxygen therapy (HBOT) has been associated with improved wound healing and lower rates of amputation in patients with diabetic foot ulcers, but data regarding the use of this modality in the treatment of nonhealing arterial ulcers is limited [88,89]. Current professional society guidelines do not include recommendations regarding the use of HBOT in CLI.…”

Section: Hyperbaric Oxygen Therapymentioning

confidence: 99%

Medical Therapy in Peripheral Artery Disease and Critical Limb Ischemia

Foley

Waldo

Armstrong

2016

Curr Treat Options Cardio Med

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Peripheral artery disease (PAD) comprises atherosclerosis of the aorta and lower extremities. Many patients with PAD are asymptomatic, while others present with intermittent claudication (IC) or critical limb ischemia (CLI). Defined as rest pain or tissue loss that persists for >2 weeks, CLI represents the most severe clinical manifestation of PAD and is associated with an increased risk of limb loss and death. Patients with PAD, including those with CLI, are underdiagnosed and undertreated. In addition to smoking cessation, medical therapy with an antiplatelet agent and statin is recommended for all patients with PAD. Regular exercise has been shown to improve walking distance and quality of life in patients with symptomatic PAD and should be incorporated into each patient's treatment plan. In patients who have CLI and in those with persistent lifestyle-limiting claudication despite optimal medical therapy and an exercise program, revascularization is indicated for limb salvage and symptom relief, respectively. Consensus guidelines currently support an endovascular first approach to revascularization in the majority of cases. Surgical procedures provide an alternative to endovascular therapy in select cases.

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Hyperbaric oxygen therapy for chronic wounds

Cited by 112 publications

References 55 publications

Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report

Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report

Seeking effective interventions to treat complex wounds: an overview of systematic reviews

Medical Therapy in Peripheral Artery Disease and Critical Limb Ischemia

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