Hypertension in Patients on Regular Hæmodialysis and After Renal Allotransplantation

Papadimitriou, M.; Chisholm, G. D.; Shackman, Ralph

doi:10.1016/s0140-6736(69)92542-2

Cited by 40 publications

(20 citation statements)

References 6 publications

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“…Blood pressure at the end of 1 Conversion: SI to traditional units-Creatinine: 1 t,mol/l z 0-0113 mg/100 ml.…”

Section: Methodsmentioning

confidence: 99%

Hypertension after renal transplantation.

Bachy¹,

Alexandre²,

Strihou³

1976

BMJ

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SummaryThe incidence of hypertension (mean diastolic pressure above 90 mm Hg) was evaluated in 85 patients with renal transplants whose follow-up ranged from 3 to 84 months.Bilateral nephrectomy had been performed in 80 recipients. The proportion of hypertensive subjects rose during the first three months, subsequently stabilised around 50-60% for up to five years, and then decreased slightly during the next two years. Over the years hypertension fluctuated so that one-third of the initially hypertensive patients became normotensive, and over one-third of the initially normotensive patients became hypertensive.The main single aetiological factor was renal failure.A significant relation between steroid dosage and blood pressure was found in only a quarter of the hypertensive patients, and in another quarter no cause could be found.

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“…Blood pressure at the end of 1 Conversion: SI to traditional units-Creatinine: 1 t,mol/l z 0-0113 mg/100 ml.…”

Section: Methodsmentioning

confidence: 99%

Hypertension after renal transplantation.

Bachy¹,

Alexandre²,

Strihou³

1976

BMJ

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“…At the end of the study, plasma potassium levels were significantly increased [42]. However, the patients in this study had received a higher dose of spironolactone than that used commonly.…”

Section: Risk Of Hyperkalemiamentioning

confidence: 81%

Mineralocorticoid receptor antagonists in dialysis patients

et al. 2016

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Mineralocorticoid receptor (MR) antagonists are known to have beneficial effects in patients with cardiovascular disease without renal failure. However, there have been few published studies on the effectiveness of MR antagonists in dialysis patients, and most of the studies were small-sized. The present review focuses on the effectiveness of MR antagonists and the risk of hyperkalemia in dialysis patients. Severe hyperkalemia due to treatment with MR antagonists in dialysis patients is not common, particularly in peritoneal dialysis (PD) patients, and the prospect of cardioprotective effects has been hopeful in both hemodialysis (HD) and PD patients. Further studies are required to establish optimal protocols for the use of MR antagonists in these patients without adverse effects.

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“…The most impressive report of this phenomenon was provided by Cohen [36] who noted a substantial increase in the prevalence of posttransplant hypertension (41-77%) following the re versal of a policy of routine pretransplant bilateral ne phrectomy at his institution [36]. Similar, but less dra matic reports of the value of bilateral nephrectomy have been provided by several other investigators [33,40,41], Rao et al [32] reported a much higher frequency of post transplant hypertension in 127 patients who were hyper tensive before transplantation (60%) than in a corre sponding group of 37 subjects who were normotensive prior to transplantation (13%) [32], This highly signifi- Values expressed as mean ± cant difference (x2 = 24.5, p < 0.001 ) emphasizes the role of the hosts own kidneys as a possible cause for posttrans plant hypertension. The role of corticosteroids in the gen esis or maintenance of hypertension following renal transplantation is controversial [31-34, 42, 43] but it seems unlikely that prednisone therapy plays any major role, at least in patients with stable renal function.…”

Section: Hypertension Following Renal Transplantationmentioning

confidence: 80%

Hypertension in Chronic Renal Failure

Russel¹

1983

Am J Nephrol

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Hypertension in Patients on Regular Hæmodialysis and After Renal Allotransplantation

Cited by 40 publications

References 6 publications

Hypertension after renal transplantation.

Hypertension after renal transplantation.

Mineralocorticoid receptor antagonists in dialysis patients

Hypertension in Chronic Renal Failure

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