Hypertonic and isotonic potassium solutions have different effects on vessel contractility resulting in differences in optimal resting tension in rat aorta

Abstract

Hypertonic and isotonic K(+ ) may produce different contractions resulting in differences in optimal resting tension in rat aorta.

Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats

“…Organ chamber studies Aortic rings were prepared and vascular reactivity was measured using our previous methods [14][15][16] . The rats were anesthetized with sodium pentobarbital (60 mg/kg, ip).…”

Lung Cancer Induces NK Cell Contractility and Cytotoxicity Through Transcription Factor Nuclear Localization

“…The tumour microenvironment (TME) is hypertonic due to high levels of inflammatory cytokines and cations ( Burgdorf et al, 2020 ). The osmolarity of the extracellular compartment has traditionally been known to affect intracellular contractility, with the hypertonic environment triggering increased contractility and vice versa ( Guan et al, 2007 ; Malek et al, 2007 ). For example, hypertonicity can trigger RhoA-dependent actin reassembly that generates contractile force in endothelial cells ( Malek et al, 2007 ).…”