Hypertriglyceridemia and Hypercholesterolemia in Human Immunodeficiency Virus-1-Infected Children Treated with Protease Inhibitors

Santos, Fortino Solórzano; Gochicoa‐Rangel, Laura; Saucedo, Gerardo Palacios; Rosales, Guillermo Vazquez; Novales, María Guadalupe Miranda

doi:10.1016/j.arcmed.2005.05.013

Cited by 24 publications

(11 citation statements)

References 22 publications

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“…The finding of a high prevalence of dyslipidemia in this population is consistent with other studies, 33–38 and the lipid mean values encountered are close to those of other samples of HIV-infected children in Mexico, 39 Brazil, 40 Spain 4 and US. 41 …”

Section: Discussionsupporting

confidence: 92%

Dyslipidemia, Diet and Physical Exercise in Children on Treatment With Antiretroviral Medication in El Salvador

Sonego

Sagrado

Escobar

et al. 2016

Pediatric Infectious Disease Journal

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Section: Discussionsupporting

confidence: 92%

Dyslipidemia, Diet and Physical Exercise in Children on Treatment With Antiretroviral Medication in El Salvador

Sonego

Sagrado

Escobar

et al. 2016

Pediatric Infectious Disease Journal

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“…Over the last few years, numerous advances in antiretroviral therapy have resulted in the improved survival and nutritional status of individuals with HIV 2. Progress in the treatment of AIDS has changed it into a chronic disease.…”

Section: Discussionmentioning

confidence: 99%

“…Highly active antiretroviral therapy (HAART) including protease inhibitors (PI) has been associated with effective and lasting reduction in HIV viral load, with a decreased incidence of opportunistic infections and an improvement in the survival, neurodevelopment, growth and quality of life of infected children 1,2. …”

Section: Introductionmentioning

confidence: 99%

Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy

Contri

Berchielli²,

Tremeschin³

et al. 2011

Clinics

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OBJECTIVE:To describe nutritional status, body composition and lipid profile in children and adolescents receiving protease inhibitors.METHODS:Fifty-nine patients, 23 treated with protease inhibitors (group 1) and 36 not using protease inhibitors (group 2). Their dietary intake, anthropometry, bioimpedance analysis and lipid profile variables were measured.RESULTS:There was no difference in nutritional status or body composition between groups at the beginning of the study. After 6 months of follow-up, there was an increase in weight and height in both groups, as well as in waist circumference and subscapular skinfold thickness. In group 2, body mass index and triceps skinfold thickness adequacy were significantly higher after 6 months of follow-up. The groups had similar energy and macronutrient intake at any time point. After 6 months, group 1 had a higher cholesterol intake and group 2 had a higher fiber intake. Triglyceride serum levels were significantly different between the groups, with higher values in G1, at any time point [G1: 153 mg/dl (30–344); 138 (58–378) versus G2: 76 mg/dl (29–378); 76 (29–378)]. After 6 months of follow-up, G1 had higher LDL-cholesterol than G2 [104 mg/dl (40–142) versus 82 (42–145)].CONCLUSION:The use of protease inhibitors, per se, does not seem to significantly interfere with anthropometric measures, body composition and food intake of HIV-infected children and adolescents. However, this antiretroviral therapy was associated with a significant increase in triglyceride and LDL-cholesterol in our subjects.

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“…The presence or the antecedent of a middle ear effusion without signs of infection was considered as chronic otitis media with effusion, and the presence or antecedent of persisting suppurative otorrhea with perforation of the tympanic membrane was considered to be chronic suppurative otitis media [30,31]. Patients in this study were from a cohort being evaluated clinically once a month, and every 3 months by means of VL and CD4+/CD8+ cell counts [21,32]. Information concerning antiretroviral treatment, including antiretroviral drugs administered prior to HAART and time on HAART when audiologic and vestibular tests were carried out, as well as adherence to treatment, was obtained from Hospital de Pediatria AIDS outpatient clinic data, from the clinical charts, and by directly questioning parents or guardians, and the patients themselves when possible.…”

Section: Hiv-1 Infection and Antiretroviral Treatmentmentioning

confidence: 99%

Audiologic and vestibular findings in a sample of Human Immunodeficiency Virus type-1-infected Mexican children under Highly Active Antiretroviral Therapy

Palacios

Montalvo

Fraire

et al. 2008

International Journal of Pediatric Otorhinolaryngology

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Hypertriglyceridemia and Hypercholesterolemia in Human Immunodeficiency Virus-1-Infected Children Treated with Protease Inhibitors

Cited by 24 publications

References 22 publications

Dyslipidemia, Diet and Physical Exercise in Children on Treatment With Antiretroviral Medication in El Salvador

Dyslipidemia, Diet and Physical Exercise in Children on Treatment With Antiretroviral Medication in El Salvador

Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy

Audiologic and vestibular findings in a sample of Human Immunodeficiency Virus type-1-infected Mexican children under Highly Active Antiretroviral Therapy

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