“…There is substantial evidence that palliative radiotherapy (RT) is effective in the management of bleeding, with reported treatment response (i.e. that bleeding would stop or diminish) varying from 45% to 100% [2] , [3] , [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] . It is, however, not clear which RT schedule, with regard to fractionation and total dose, is most ‘optimal’ (with as less fractions and less toxicity for the patient and as much as possible effect on symptom control) to manage bleeding.…”