Hypomagnesemia As A Marker For Preterm Labour And Its Association With Socio Economic Status.

Bhat, Shakura; Waheed, Arfat; Chisti, Tasleema; Habib, Huma

doi:10.5455/jib.20120501030110

Cited by 4 publications

(12 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…8,9 However, it was lower in preterm group as compared to study conducted by Bhat et al, (28.63 years). 7 The difference can be explained due to early age of marriage and lesser use of contraceptives methods in our study.…”

Section: Discussionmentioning

confidence: 57%

“…Bhat et al, found patients with preterm labour belonging to low socioeconomic class were significantly higher than the middle and higher socioeconomic classes (58% in preterm labour patients and 45% in term, p<0.05). 7 Mahmoud et al, also found that in preterm labour group lower socioeconomic class was significantly higher than the middle and upper socioeconomic classes. 8 Patients belonging to low socioeconomic classes have stressful lifestyle, inaccessible medical care and diet deficient in micronutrients including magnesium.…”

Section: Discussionmentioning

confidence: 91%

“…Bhat et al found mean serum magnesium level of 1.37±0.055, 1.35±0.065 and 1.31±0.060mg/dL respectively in preterm gestational age groups 28-30 weeks, 31-33 weeks and 34-36 weeks with lowest levels at 34-36 weeks period of gestation. 7 Mahmoud et al, found that in 28-30 weeks gestational age group level was 1.843±0.70mg/dL, 31-33 weeks 1.309±0.369mg/dL and 34-36 weeks 1.23±0.28mg/dL. 8 With these studies it was found that magnesium level decreases with increasing gestational which may be due to physiological hemodilution in pregnancy contributing to the onset of preterm labour.…”

Section: Discussionmentioning

confidence: 93%

“…6 Bhat et al, found that patients in preterm labour group had a significantly depressed mean serum magnesium level as compared to normal pregnancy (1.34 mEq/L vs. 1.87 mEq/L; p<0.001). 7 Mahmoud et al, found that patients with preterm labour had significantly reduced serum magnesium level (mean 1.55mg/dL versus 1.81mg/dL) for those who delivered at term (p<0.032). 8 Jenabi et al, also found positive association between maternal serum magnesium levels and preterm labour.…”

Section: Discussionmentioning

confidence: 98%

“…Our findings were similar to the observations of Bhat et al, Mahmoud et al, and Shaikh et al, who reported percentage of patients with preterm labour having history of muscle cramps as 89%, 73% and 46.7% respectively. [7][8][9] Neuromuscular hyperexcitability is an initial problem cited in individuals who have magnesium deficiency resulting in muscle cramps and uterine hyperactivity leading to premature onset of labour. 13 In our study low birth weight neonates were significantly more in patients with preterm labour with percentage of 60% and 11% in patients with term labour.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

The study of association between maternal serum magnesium levels and preterm labour in a tertiary care hospital

Anand¹,

Hak²,

Prashar³

et al. 2019

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Serum magnesium level in pregnancy is a valuable tool to find out preterm onset of labour. In the asymptomatic group, greater surveillance and administration of steroids, tocolytics and transfer to a higher centre wherever necessary has to be done with mothers with low serum magnesium level. The objective of the study is to find association between serum magnesium levels and women with preterm labour, and to compare these values with those patients who have a term delivery.Methods: The subjects included 100 pregnant women with preterm labour (cases) between 28 and 37 weeks gestation (Group A) and similar number of pregnant women with term labour (controls) between 37 and 40 weeks (Group B). Inclusion criteria for cases was singleton pregnancy, painful uterine contractions more than two in 30 minutes, intact fetal membranes, cervical dilatation (at least 1 cm) and effacement (80%). Serum magnesium levels were done in both the groups. Patients were followed until delivery. Routine antenatal investigations were done. Serum levels of magnesium were estimated by Erba’s semi auto-analyser.Results: 62% patients in Group A were from rural areas. More patients in Group A (70%) were from low socioeconomic class. More women in Group A were anaemic (44%). Mean value of hemoglobin in Group A was 9.93gm/dL. More patients in Group A had muscle cramps (89%). VLBW (<1500gm) neonates were more in Group A (21%). Also, LBW (1500-2499gm) neonates were more in Group A (60%). Mean neonatal birth weight in Group A (1907.3gm) was less. Neonatal morbidity and mortality was observed significantly more in Group A. Mean serum magnesium was less in Group A. Mean serum magnesium levels in primi and multigravida patients were less in Group A. Moreover, mean serum magnesium levels were less in urban and rural patients in Group A. Mean serum magnesium levels were less in normal and overweight patients in Group A. Also, mean serum magnesium levels were less in patients with cervical dilatation <3cm and >3cm in Group A.Conclusions: Low maternal serum magnesium level is associated with preterm labour. Patients with preterm labour have significantly low serum magnesium level when compared with labour at term.

show abstract

Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

The study of association between maternal serum magnesium levels and preterm labour in a tertiary care hospital

Anand¹,

Hak²,

Prashar³

et al. 2019

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

show abstract

Serum magnesium levels in preterm labour in relation to socio-economic status

Anand

Jaggi

Bala

2022

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Serum magnesium level in pregnancy is a valuable tool to find out preterm onset of labour. In the asymptomatic group, greater surveillance and administration of steroids, tocolytics and transfer to a higher centre. In this study, low maternal serum magnesium level was associated with preterm labour. The values were also lower in women with low socio-economic status.Methods: The subjects included 100 pregnant women with preterm labour (cases) between 28 and 37-week gestation (group A) and similar number of pregnant women with term labour (controls) between 37 and 40 weeks (group B). Inclusion criteria for cases was singleton pregnancy, painful uterine contractions more than two in 30 minutes, intact fetal membranes, cervical dilatation (at least 1 cm) and effacement (80%). Serum magnesium levels were done in both the groups. Patients were followed until delivery. Routine antenatal investigations were done. Serum levels of magnesium were estimated by Erba’s semi auto-analyser.Results: 62% patients in group A were from rural areas. More patients in group A (70%) were from low socioeconomic class. More women in group A were anaemic (44%). Mean value of hemoglobin in group A was 9.93 g/dl. More patients in group A had muscle cramps (89%). VLBW (<1500 g) neonates were more in group A (21%). Also, LBW (1500-2499 g) neonates were more in group A (60%). Mean neonatal birth weight in group A (1907.3 g) was less. Neonatal morbidity and mortality were observed significantly more in group A. Mean serum magnesium was less in group A.Conclusions: Low maternal serum magnesium level is associated with preterm labour. Patients with preterm labour have significantly low serum magnesium level when compared with labour at term. The values were also lower in women with low socioeconomic status.

show abstract

Preterm Labour

Ropeta

Ali

2018

TPMJ

View full text Add to dashboard Cite

Background: Spontaneous preterm labor that is labor before 37 weeks ofgestation is the main cause of preterm delivery. With increasing gestation the level of Serummagnesium levels decreases. Magnesium inhibits uterine contractions by antagonizing calcium.Hypomagnesaemia also causes hyper excitability of neuromuscular junction bringing in musclecramps and uterine hyperactivity. Objectives: To determine the mean serum magnesium levelsin women presenting with preterm labor. Study Design: Cross Sectional Study. Location andduration of study: Ziauddin University Hospitals, Karachi from 8th December 2015 to 7th June2016. Methodology: Total 40 women of age 18-40 years having singleton pregnancy between28-36 weeks gestation with established preterm labor having cervical dilatation less than 3cm.were included. 5ml blood was collected and analyzed. Outcome in terms of Mean StandardDeviation were noted. Descriptive statistics were applied. Stratification was done using studentt-test and ANOVA where appropriate. The p-value ≤0.05 was considered as significant. Results:The mean age was 26.25±2.38 years. Mean gestational age was 32.77±2.11 weeks. Meancervical dilatation was 1.85±0.39 cm. Mean serum magnesium level was found 1.43±0.25 mg/dl. The results showed that there was significant difference in mean serum magnesium level forgestational age but not significant for age, cervical dilatation, parity and gravida. Conclusion:The results showed that serum magnesium level reduced with increased gestational age.Preterm labor can be predicted by serum magnesium levels.

show abstract

Hypomagnesemia As A Marker For Preterm Labour And Its Association With Socio Economic Status.

Cited by 4 publications

References 15 publications

The study of association between maternal serum magnesium levels and preterm labour in a tertiary care hospital

The study of association between maternal serum magnesium levels and preterm labour in a tertiary care hospital

Serum magnesium levels in preterm labour in relation to socio-economic status

Preterm Labour

Contact Info

Product

Resources

About