Abstract:inclusion criteria for methotrexate treatment of tubal ectopic pregnancies are: Haemodynamically stable, not ruptured, serum hCG of <4000 IU/L on day 0 or hCG ratio at 48 h of >0.8 (hCG 48 h:hCG 0 h), normal haematological, liver and renal blood profiles, ectopic mass <4 cm, not live ectopic and good compliance with treatment. Second dose of methotrexate is considered if there is suboptimal fall of hCG (<15% at day 7 follow up of methotrexate). Patients who develop significant pain, signs of haemoperitoneu… Show more
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