2018
DOI: 10.1101/275719
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Enterococcus faecalisAHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses NF-kB activation in human gut epithelial cells

Abstract: 16Enterococcus faecalis is an early coloniser of the human infant gut and contributes to the development 17 of intestinal immunity. To better understand the functional capacity of E. faecalis we constructed a 18 broad host range RP4 mobilisable vector, pEHR513112, that confers chloramphenicol resistance and 19 used a metaparental mating approach to isolate E. faecalis AHG0090 from a faecal sample collected 20 from a healthy human infant. We demonstrated that E. faecalis AHG0090 is genetically tractable and 21 … Show more

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