<i>in vitro</i> Antioxidant Activity and Total Polyphenolic Content of <i>Cyperus rotundus</i>  Rhizomes

Nagulendran, KR; Velavan, S; Mahesh, R.; Begum, V. Hazeena

doi:10.1155/2007/903496

Cited by 135 publications

(113 citation statements)

References 18 publications

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“…Hidrogen peroxide can readily cross cell membranes and once inside the cell, the hydrogen peroxide can react with Fe 2+ ions to form hydroxyl radicals which may cause toxic effects. Therefore, it is advantageous to biologically cells which control the amount of hydrogen peroxide (Nagulendran et al, 2007). Thus, the fractions of CHLF and HF with higher antioxidant activity have shown to be promising in the study of antioxidant activity in the scavenging of H 2 O 2 .…”

Section: Hydrogen Peroxide Scavenging Activity (Hps)mentioning

confidence: 99%

Determination of antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfuit) seeds extracts

Burci¹,

Silva²,

Oliveira³

et al. 2015

J. Med. Plants Res.

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Plants and their parts are a part of life in many brazilian communities, as observed in the jackfruit. The jackfruit seeds are consumed usually as roasted, boiled, steamed, and are eaten as a snack. The present study was carried out to identify the antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus seeds using different screening tests. Total antioxidant activity was determined by ferric thiocyanate method (FTC), which was shortly followed by complexing of fosfomolybdenium method (FSB) determined in sequence with total reductive capability (TRC), hydrogen peroxide scavenging activity (HPS), DPPH free radical scavenging activity, and Total phenolic content (TPC) by Folin-Ciocalteu reagent assay method. The percentage of inhibition linoleic acid peroxidation by CEE (ethanolic extract), HF (hexanic extract), CHLF (chloroform extract) and EAF (ethyl acetate extract) (90.53, 70.23, 68.72 and 92.03%, respectively), in method using prussian blue antioxidant potential for EAF (89,05%) presented antioxidant activity greater than the standard rutin (82.3%). Highest total antioxidant activity was exerted by the ethanolic extract of A. heterophyllus seeds, and lowest by its EAF (188.83%). In evaluating the antioxidant activity by the hidrogen peroxide scavenging activity, it was observed that the CHLF and HF extracts showed scavenging activity above 50% (83.3 and 83.5%, respectively). The EC 50 (free radical scavenger) values of CEE, HF, CHLF and EAF were 76.71, 399.64, 534.83 and 65.51 μg/ml, respectively, and the highest total phenolic content appeared to be present in 125 µg/ml of EAF. The results of all the sources were found to be highly significant. Further investigation for isolation and identification of the phytoconstituents responsible for antioxidant activity is desirable. A. heterophyllus seeds in the regular diets could improve the antioxidant status of human beings.

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Section: Hydrogen Peroxide Scavenging Activity (Hps)mentioning

confidence: 99%

Determination of antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfuit) seeds extracts

Burci¹,

Silva²,

Oliveira³

et al. 2015

J. Med. Plants Res.

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“…Flavonoids and other polyphenolic compounds inhibit free radicals production and lipid peroxidation. The pistachio extract is rich in natural antioxidants, and thus, can be used as a therapeutic agent for diseases associated with the aging process and free radicals, such as neural degeneration (28,29). Free radicals play an important role in nerve damage caused by stroke and Alzheimer's disease (30).…”

Section: Discussionmentioning

confidence: 99%

“…Free radicals play an important role in nerve damage caused by stroke and Alzheimer's disease (30). Hence, pistachios may be used as a beneficial factor for the treatment of these diseases and improvement in learning and memory (21,22,28). Various vitamins, particularly vitamins B1, B2, B6, E, and C, in addition to improving physical strength, increase nervous power, and therefore, are used for the treatment of central nervous system diseases (31).…”

Section: Discussionmentioning

confidence: 99%

Effect of the hydroalcoholic extract of pistachio on avoidance learning in male Wistar rats

Salari

Baloochi

Ali

et al. 2014

JOHE

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Received: December 2015, Accepted: January 2016Background: Pistachio is a plant that has long been cultivated in different parts of Iran. Pistachios are very nutritious and contain vitamins E and B, flavonoids, antioxidants, and carotenoids. Since the pistachio is effective in the treatment of some neurological disorders and is indigenous to Iran and considering the substantial use of this nut, it is necessary to investigate its effects on cognitive functions of the brain. This study aimed to investigate the effect of the hydroalcoholic extract of the pistachio on avoidance learning in rats. Materials and Methods: In this experimental study, 40 male Wistar rats (200-250 g body weight and 2-3 months of age) were divided into 4 groups. Dimethyl sulfoxide (DMSO) 2.5% (vehicle) and hydroalcoholic extract of the pistachio (10, 50, and 100 mg/kg/day) were administered by gavage for 14 days. Avoidance learning test was performed using the shuttle box. Results:The results of this study indicated a significant increase in the latency to enter the dark room in the groups receiving different doses of pistachio extract compared to vehicle treated group. Moreover, in the treated groups, time spent in the dark room was decreased compared to the vehicle group. The comparison of different doses of pistachio extract demonstrated that 100 mg/kg was more effective than 10 and 50 mg/kg of the extract. Conclusions:The results of this study indicated that treatment of rats with pistachio extract, which is rich in vitamins, flavonoids, and antioxidant compounds, can improve learning and memory.

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“…The indigenous antioxidants may be useful in preventing the deleterious consequences of oxidative stress and there is increasing interest in the protective biochemical functions of natural antioxidants contained in herbs and medicinal plants (Nagulendran et al, 2007). There are different experimental methods to evaluate free radical scavenging activity of a plant extract or product and one such method is evaluating the ability of plant extract to scavenge of DPPH radicals.…”

Section: In Vitro Free Radical Scavenging Activity:-mentioning

confidence: 99%

A Comparative Study on Quantitative Phytochemical Analysis and in Vitro Free Radical Scavenging Activityof Various Solvent Extracts of Tetracera Akara(burm. F.) Merr., an Ethnomedicinal Plant Used by Kani Tribe of Kerala.

Nair¹,

Suja²,

Aneeshkumar³

et al. 2017

IJAR

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in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes

Cited by 135 publications

References 18 publications

Determination of antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfuit) seeds extracts

Determination of antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfuit) seeds extracts

Effect of the hydroalcoholic extract of pistachio on avoidance learning in male Wistar rats

A Comparative Study on Quantitative Phytochemical Analysis and in Vitro Free Radical Scavenging Activityof Various Solvent Extracts of Tetracera Akara(burm. F.) Merr., an Ethnomedicinal Plant Used by Kani Tribe of Kerala.

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