o‐Benzenedisulfonimide as a Reusable Brønsted Acid Catalyst for Ritter‐Type Reactions

Abstract

Reactions between various benzyl alcohols or tert-butyl alcohol and nitriles were carried out in the presence of catalytic amounts (usually 10-20 mol-%) of o-benzenedisulfonimide as a Brønsted acid catalyst; the reaction conditions were mild and the yields of amides were good. The catalyst

Reaction of Olefins with Nitriles under Solvent-Free Conditions Using Molecular Iodine as a Catalyst in the Presence of Water

“…2.1 General NMR spectra were obtained using a 300 MHz FT-NMR spectrometer Bruker DPX-300 with Me 4 Si as an internal standard and CDCl 3 as a solvent. IR spectra were recorded on a JASCO FT/IR-230 spectrometer.…”

Ritter Reaction: Recent Catalytic Developments

“…[6] The nitriles were generally employed as the solvents, but it is worth noting that the reactions could also be carried out without solvent, by use of stoichiometric amounts of nitriles, without the yields being affected. When benzhydrol (4a) was used in acetonitrile at reflux, the corresponding amide 5a was isolated in 87 % yield.…”

Starbon®400-HSO3: A green mesoporous carbonaceous solid acid catalyst for the Ritter reaction

“…Over the years, improved processes have been reported for the synthesis of N-alkyl amides, via acid catalyzed Ritter reaction under homogeneous [6,7] and heterogeneous conditions [8,9]. Brønsted acid ionic liquids [10] and organic acids, such as 2,4-dinitrobenzenesulfonic acid (DNBSA) [11], obenzenedisulfonimide [12] and pentafluorophenyl ammonium triflate (PFPAT) [13] have also been recently applied as metal-free catalysts in the Ritter reaction.…”