Staphylococcus lentus Sinusitis: A New Sinonasal Pathogen

Abstract

Background: The pathogens most commonly associated with acute bacterial rhinosinusitis include Streptococcus pneumonia, Haemophilus influenza, and Moraxella catarrhalis. The pathogens most commonly associated with chronic rhinosinusitis include Staphylococcus aureus and various anaerobic organisms, including Prevotella, Porphyromonas, Fusobacterium, and Peptostreptococcus. This case report illustrates a case of chronic rhinosinusitis associated with the Staphylococcus lentus organism, a well-known animal pathogen that has never been documented in the sinonasal cavity before. Methods: The medical records of an adult patient who presented to the otolaryngology office were reviewed. The literature available was reviewed. Results: A 62-year-old man presented with chronic rhinosinusitis refractory to medical management. He was taken to the operating room for functional endoscopic sinus surgery and cultures were obtained, which returned positive for Staphylococcus lentus. He had no known animal contacts at home or work. He improved with surgery and appropriate antibiotic therapy. Conclusions: Staphylococcus lentus has never before been reported as a human pathogen in the sinonasal cavities. Otolaryngologists must routinely obtain cultures of mucus or tissue during sinus surgery in order to ensure appropriate antibiotic treatment after surgery and resolution of patient symptoms.

Characterization of florfenicol resistance genes in the coagulase-negative Staphylococcus (CoNS) isolates and genomic features of a multidrug-resistant Staphylococcus lentus strain H29

“…S. lentus was traditionally considered to be an animal pathogen and has been isolated from a wide range of pets, farm animals, wild animals, and retail meats [ 24 ]. S. lentus has also been identified as the causative organism in several serious human infections, including sinusitis , endocarditis, peritonitis, septic shock, urinary tract infection, and wound infections, and its clinical significance is apparently increasing [ 25 – 27 ]. In this work, in addition to detecting the florfenicol resistance levels and resistance genes of 39 Staphylococcus isolates from poultry and seafood, we also investigated the molecular mechanism of florfenicol resistance of a S. lentus strain with high level florfenicol resistance isolated from a hen.…”

Morel (Morchella spp.) intake alters gut microbial community and short-chain fatty acid profiles in mice

“…These findings supported our results that morel intake enriched P. distasonis ( Supplementary Figure S2A ; Figure 3 ), increased the SCFAs ( Figure 4 ; Supplementary Figure S3 ; Supplementary Table S2 ), leading to the decrease in food intake ( Supplementary Figure S1D ) and weight loss ( Supplementary Figure S1C ). Staphylococcus lentus has recently been identified as a pathogen in the sinonasal cavities ( 52 ) and is also a commensal bacterium in the skin and gut of animals, associated with skin infections ( 53 , 54 ), following morels intervention, there was a decrease in its levels ( Supplementary Figure S2C ).…”

Staphylococcal species composition in the skin microbiota of domestic pigeons (Columba livia domestica)

“…lentus . This bacterium can cause several serious human infections, including sinusitis, endocarditis, peritonitis, septic shock, urinary tract infection and wound infections [ 34 – 36 ]. Other CoNS species, such as S .…”