Ibopamine provocative test and glaucoma: Consideration of factors that may influence the examination

Abstract

The Ibopamine provocative test may be an auxiliary test in glaucoma diagnosis. Concurrent use of prostaglandin analogues reduces the test's sensitivity.

Baseline factors predicting the risk of conversion from ocular hypertension to primary open-angle glaucoma during a 10-year follow-up

“…The ability of the ibopamine test result in discriminating between converters and non-converters was very poor, with a sensitivity of 69% and a specificity of 41.4%, suggesting that a large proportion of the OHT subjects had a reduced outflow of the aqueous humor. Although several previous authors have demonstrated that the ibopamine test has high accuracy in differentiating glaucomatous eyes from normal 46 and glaucoma suspect eyes, 47 our data show that the positivity of the ibopamine test has no predictive value for the development of glaucoma. The results of the present study suggest that the ibopamine provocative test seems to be efficient in indicating the actual health status of the trabecular meshwork, but it seems unable to predict the evolution of the glaucomatous disease.…”

Avaliação do comportamento da pressão intraocular em pacientes com glaucoma primário de ângulo aberto assimétrico submetidos ao teste provocativo da ibopamina

“…Todavia, em outro estudo mais recente, esta relação não foi estatisticamente significante, provavelmente devido ao fato de não ter sido feita uma seleção rigorosa dos pacientes em relação à diferença no MD (21) .…”

“…Todavia, esta relação ibopamina e análogos da prostaglandina, ainda necessita de mais estudos, uma vez que há trabalhos que indicam que o uso destas drogas levam a uma diminuição da sensibilidade do teste provocativo da ibopamina (21) .…”

Correlation between the ibopamine provocative test and the diurnal tension curve in glaucoma patients

“…Several authors have achieved good sensitivity and specificity with the ibopamine provocative test for glaucoma (7)(8)(9)(10)(11) . Glaucoma patients typically have larger intraocular pressure fluctuations compared to the normal population (12)(13)(14) .…”