ICU-Acquired Pneumonia With or Without Etiologic Diagnosis

Giunta, Valeria; Ferrer, Miquel; Esperatti, Mariano; Ranzani, Otávio T.; Saucedo, Lina María; Bassi, Gianluigi Li; Blasi, Francesco; Torres, Antoni

doi:10.1097/ccm.0b013e31828a453b

Cited by 22 publications

(20 citation statements)

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“…2 The microbiologic evaluation was extensively addressed in previous reports. 15,16 Briefl y, we collected at least one lower respiratory airways sample (sputum in nonintubated patients or tracheobronchial aspirates in those intubated), and BAL if possible, within the fi rst 24 h of inclusion. Blood cultures and cultures from pleural fluid if puncture was indicated were also taken.…”

Section: Defi Nition Of Pneumonia Microbiologic Processing and Antimentioning

confidence: 99%

“…a In two patients without COPD, more than one Enterobacteriaceae was identifi ed. TNF-a , pg/mL 9 (6-16) 7 (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) .43 7 (5-10) 11 (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) .12…”

Section: Outcome Variablesmentioning

confidence: 99%

“…36 We have suggested that some of these cases with negative microbiology might also represent, at least in part, fl uid overload added to the underlying infl ammatory process potentially mimicking pneumonia. 15 Th ird, the lack of association of COPD with survival in patients with nonventilator ICUAP should be taken cautiously because of the smaller number of patients analyzed. However, the shape of the survival curves was clearly diff erent from that of patients with VAP ( Fig 3 ).…”

Section: Copd As Predictor Of Mortality In Patients With Icuapmentioning

confidence: 99%

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Impact of COPD in the Outcome of ICU-Acquired Pneumonia With and Without Previous Intubation

Rinaudo

Ferrer

Terraneo

et al. 2015

Chest

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Section: Defi Nition Of Pneumonia Microbiologic Processing and Antimentioning

confidence: 99%

Section: Outcome Variablesmentioning

confidence: 99%

Section: Copd As Predictor Of Mortality In Patients With Icuapmentioning

confidence: 99%

See 1 more Smart Citation

Impact of COPD in the Outcome of ICU-Acquired Pneumonia With and Without Previous Intubation

Rinaudo

Ferrer

Terraneo

et al. 2015

Chest

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“…On the other hand, the clinical course of patients already admitted to the ICU, for a variety of reasons, may be complicated by the occurrence of a LRTI: these patients are considered to have an ICU-acquired pneumonia (ICUAP). ICUAP may affect patients who are undergoing mechanical ventilation or during spontaneous breathing [4, 5]. Hence, this definition includes both ventilator-associated pneumonia (VAP) and non-ventilator ICU-acquired pneumonia (NV-ICUAP).…”

Section: Introductionmentioning

confidence: 99%

Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project

Pascale

Ranzani

Nseir³

et al. 2017

ERJ Open Res

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The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects.A European network for ICU-related respiratory infections (ENIRRIs), supported by the European Respiratory Society, has been recently established, with the aim at studying all respiratory tract infective episodes except community-acquired ones. A multicentre, observational study is in progress, enrolling more than 1000 patients fulfilling the clinical, biochemical and radiological findings consistent with a LRTI. This article describes the methodology of this study. A specific interest is the clinical impact of non-ICU-acquired nosocomial pneumonia requiring ICU admission, non-ventilator-associated LRTIs occurring in the ICU, and ventilator-associated tracheobronchitis. The clinical meaning of microbiologically negative infectious episodes and specific details on antibiotic administration modalities, dosages and duration are also highlighted. Recently released guidelines address many unresolved questions which might be answered by such large-scale observational investigations. In light of the paucity of data regarding such topics, new interesting information is expected to be obtained from our network research activities, contributing to optimisation of care for critically ill patients in the ICU.

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“…Azoknál a betegeknél, akiknél nem alakult ki fertőzés, szignifi kánsan rövi-debb ideig tartott a gépi lélegeztetés, illetve az antimikrobiális kezelés. Ebben a csoportban a túlélési görbe is kedvezőbb volt [20]. Karapanagiotou és mtsai is ha sonló eredményekről számolnak be [14].…”

Section: Preoperatív Jellemzők éS a Fertőzésunclassified

Bakteriális infekciók májátültetés után

et al. 2015

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Bevezetés: A szerzők a májátültetést követően kialakult mikrobás fertőzéseket, a mintavételek eredményeit, a multidrug-rezisztencia incidenciáját vizsgálták a hazai betegek körében. Célkitűzés: Tanulmányozták a bakteriális fertőzés kialakulásának kockázati tényezőit, az infekciókhoz kapcsolódó szövődmények előfordulását, lefolyását, és részletes kórokozó-spektrumelemzést végeztek. Módszer: 2003-2012 között májátültetett 408 beteg adatait (281 bakterioló-giai tenyésztést) vizsgálták. Eredmények: A 408 beteg közül 70 betegnél (17%) észleltek klinikai tünetekkel járó fertőzést. A tenyésztési lelet 58 betegnél (14,2%) pozitív, 12 betegnél (2,9%) negatív volt. Hét esetben (12,1%) alakult ki cholangitis, 17 esetben (29,3%) fordult elő hasűri és 28 esetben (48,3%) pulmonalis eredetű fertőzés. Posztoperatív fertőzés gyakrabban lépett fel kezdeti csökkent graftműködés, akut veseelégtelenség, epeúti szövődmény és hasű-ri vérzés mellett. Infekció kialakulása esetén az 1, 3 és 5 éves betegtúlélés 70%, 56% és 56% volt, míg infekció nélkül ez 94%, 87%, 85% volt (p<0,001). A kitenyészett baktériumok 56%-ánál találtak multidrug-rezisztenciát, viszont nem volt szignifi káns különbség a multidrug-rezisztencia pozitív és negatív baktériummal fertőzött csoportok egyéves betegtúlélése között (70,2% mindkettő). Következtetések: Az infekciókontroll, a multidrug-rezisztens kórokozók menedzselése a preventív, higiéniai, izolációs elvek kialakítását, betartását, valamint műtéttechnikai, transzfúziós, antibiotikus stratégiák, folyamatok fejlesztését kell, hogy megcélozza, szakmai csapatmunka keretén belül. Orv. Hetil., 2015, 156(34), 1366-1382. Kulcsszavak: májátültetés, posztoperatív fertőzés, multidrug-rezisztencia, túlélés, szepszis Bacterial infection after orthotopic liver transplantationIntroduction: The authors reviewed the prevalence of postoperative infections, the results of bacterium cultures, and the incidence of multidrug resistance in their liver transplanted patients during a period between 2003 and 2012. Aim: The aim of this study was to analyse risk factors and colonisations of bacterial infections. Method: The fi les of 408 patients (281 bacterium cultures) were reviewed. Results: Of the 408 patients 70 had a postoperative infection (17%); 58 patients (14.2%) had positive and 12 patients (2.9%) negative bacterial culture results. Cholangitis was found in 7 cases (12.1%), abdominal infection in 17 cases (29.3%), and pulmonal infection in 28 cases (48.3%). Postoperative infection was more frequent in patients with initial poor graft function, acute renal insuffi ciency, biliary complication, and in those with intraabdominal bleeding. The 1-, 3-and 5-year cumulative survival of patients who had infection was 70%, 56% and 56%, respectively, whereas the cumulative survival data of patients without infection was 94%, 87% and 85%, respectively (p<0.001). Multidrug resistance was found in 56% of the positive cultures, however, the one-year survival was not different in patients who had multidrug resistance positive and negative...

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ICU-Acquired Pneumonia With or Without Etiologic Diagnosis

Cited by 22 publications

References 50 publications

Impact of COPD in the Outcome of ICU-Acquired Pneumonia With and Without Previous Intubation

Impact of COPD in the Outcome of ICU-Acquired Pneumonia With and Without Previous Intubation

Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project

Bakteriális infekciók májátültetés után

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