Identification and Evolutionary Analysis of the Widely Distributed CAP Superfamily in Spider Venom
Hongcen Jiang,
Yiru Wang,
Guoqing Zhang
et al.
Abstract:Venom plays a crucial role in the defense and predation of venomous animals. Spiders (Araneae) are among the most successful predators and have a fascinating venom composition. Their venom mainly contains disulfide-rich peptides and large proteins. Here, we analyzed spider venom protein families, utilizing transcriptomic and genomic data, and highlighted their similarities and differences. We show that spiders have specific combinations of toxins for better predation and defense, typically comprising a core to… Show more
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