2020
DOI: 10.21203/rs.3.rs-31517/v1
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Identification and Validation of a Predictive Immune-Related Genes Signature for the Prognosis of Cholangiocarcinoma

Abstract: Background: Immune-related genes (IRGs) play a crucial role in the initiation and progression of cholangiocarcinoma (CCA). However, immune signatures have rarely been used to predict prognosis of CCA. The aim of this study was to construct a novel model for CCA to predict survival based on IRGs expression data. Methods: The gene expression profiles and clinical data of CCA patients from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database were integrated to establish and validate prognosti… Show more

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