Identification of a novel HLA‐A allele, HLA‐A*02:590, in a Korean individual

Abstract

A*02:590 differs from A*02:01:01:01 by a nucleotide substitution at codon 152 (GTG → GCG) with amino change.

HLA‐A*02:687, a novel allele identified by sequence‐based typing in cord blood from a Korean woman

“…In particular, HLA‐A*02 is a very common allotype in the Korean population with a frequency of 28.50% . In the Korean population, 11 A*02 alleles have been reported and A*02:01 is the most frequent . Here, we report a newly identified A*02:687 , a variant of A*02:01:01:01 allele, that was detected in a cord blood unit donated by a Korean woman.…”

“…2 In the Korean population, 11 A*02 alleles have been reported and A*02:01 is the most frequent. [2][3][4][5] Here, we report a newly identified A*02:687, a variant of A*02:01:01:01 allele, that was detected in a cord blood unit donated by a Korean woman. The HLA-A, -B, and -DRB1 alleles of the cord blood sample were genotyped using sequence-based typing (SBT) for cord blood registry (CHA Medical Center Cord Blood Center, South Korea).…”