Abstract. Bone drilling manipulation often occurs in the orthopaedic surgery. By statistics, nowadays, about one million people only in Europe need such an operation every year, where bone implants are inserted. Almost always, the drilling is performed handily, which cannot avoid the * Corresponding author e-mail: george@imbm.bas.bg. Unauthenticated Download Date | 5/9/18 11:41 PM 52 G. Boiadjiev, R. Kastelov, T. Boiadjiev, K. Delchev, K. Zagurski subjective factor influence. The question of subjective factor reduction has its answer -automatic bone drilling.The specific features and problems of orthopaedic drilling manipulation are considered in this work. The automatic drilling is presented according the possibilities of robotized system Orthopaedic Drilling Robot (ODRO) for assuring the manipulation accuracy, precision, reliability and safety.